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Ovaries

Son 140

QuestionAnswer
The ovarys are the only abdominal organ not covered by? Peritoneum
During fetal life they are located in the? Lumbar region near the Kidney
What is the ovary location? Posterior to uterus at level of cornu.Lie medial to external iliac vessels. Anterior to the internal vessels.Mesovarioan location
Regions of the ovaries Cortex and central medulla
Outer region or Cortex of the ovary consists of? Primarily of follicles in various stages of development.
Cortex is covered by? A layer of dense connective tissue, the tunica albuginea ( cover the cell) and a thin layer of cells, the germinal epithelium
Central medulla is composed of? Connective tissue containing blood, nerves, lymphatic vessels and some smooth muscle at the region of the hilum
Vascular supply ( dual blood supply) Arterial and Venous
Arterial blood supply 1. Ovarian artery,which is a branch off the abdominal aorta immediately below the renal arteries. 2. Adnexal branch of uterine artery
Venous blood supply Plexus which lies posterior to the uterus, ovarian veins arise from the venous plexus. Rt vein drains to IVC Lt vein drains to LRV
Premenarche Ovary (before menstral cycle) Mean: 3cm3 Volume Range: 0.2-9.1cm3
Menstruating Ovary Mean: 9.8cm3 3x2x2cm Volume Range: 2.5-21.9cm3
Postmenopausal Ovary Mean Volume: 5.8cm3 2x1.5x0.5cm Volume Range: 1.2-14.1cm3
They atrophy due to estrogen decrease Postmenopausal ovary
Ovarian Volume Formula V=HxWxL/2 or Vcm3=LxWxAP diameter x 0.53
Doppler of ovarian vessels Resting state:high impedance waveform Benign mass high resistance doppler flow Malignant mass low imedance w/resistive index less than .4 & pulsatility index 1.0
Doppler Formula Resistive RI=systolic-diastolic/systolic
Doppler formula Pulsatility PI=Systolic-Diastolic/Mean velocity
Benign has a high resistance waveform
Malignant has a low impedance waveform
Measurable blood flow to the ovaries varies depending upon? menstrual cycle
PT w/normal menstrual cycles are best scanned in the first? 10 days of cycle
1st 7days of menstrual flow Best time for measurments,index is? Highest
Signs that are worrisome for malignancy? Intratumral vessels Low resistance flow Absence of normal diastolic notch in the doppler waveform
Color doppler is used to localize flow for Pulse doppler
Pulsed doppler can be used to investigate the Adnexal branch of uterine artery, ovarian artery, or intratumoral flow
Color doppler, some studies suggest Peripheral vascularization appear to be more common in ? Benign tumors whereas malignant tumors tend to have more centrally located vessles.
Peripheral is found around the Tumor
Central Distribution shows blood flow in the center of tumor
Color doppler central distribution of small arteries within an ovarian mass amy be an important factor in Malignancy
Detection of ovarian cancer 1.Annual rectovaginal pelvic exam 2.CA 125 serum test 3. transvaginal ultrasound
Tumor Marker present in 80% of epithlial cancers
Simple cyst criteria for Benign cystic ovarian masses? Smooth, well-defined borders, no internal echos & posterior enhancment. Measure <5cm & regress
Result from hormonal function of ovary, common ovarian enlargment in young women & Hormonal therapy used Functional Ovarian Cyst
Functional Cyst are: Follicular, Corpus luteum, Corpus luteum of pregnancy & Theca lutein cyst.
Result form nonrupture of dominant follicle/failure of atersia. Simple cyst,unilateral,go away on there own Follicular cyst
Result form graafian follicle w/in hr of ovulation. 1-10cm hypo w/irregular thick borders around central anechoic area internal echo Results from intracystic hemorrhage Asymptomatic, unless ruptures Corpus Luteum cyst
Persist after fertilization, 3cm or more. Resolve 16 wks. Doppler reveals prominent diastolic flow Peripheral rim " ring of fire" secreates progestron Corpus Luteum of pregnancy
Largest Functional cyst,result from over stimulation & high level HGC in blood. Regress after HGC removed multilocular,thin walled, bilateral 3-20cm Theua Lutein cyst
Molar pregnancy can cause a Theca cyst
Internal hemorrhage in follicular or corpus cyst. Endovaginal best image acute, hyperechoic & may mimic solid mass. W/time can look complex, clotted blood is echogenic & fluid level Hemorrhagic Cyst
Other Benign ovarian cysts Epithelial inclusion, Paraovarian, Peritoneal inclusion,Endometrioma
Arises from superfical cortex Small up to 10cm, Mostly in postmenopausal women Epithelial Inclusion cyst
Arise broad ligament, 10% adnexal masses Multiple, round or ovoid(NOT surrounded by ovarian tissue) Any age common in 30-40s can't locate point of orgin Paraovarian
Normal ovarian fluid trapped by peritoneal adhesion/scare tissue. Mostly premenopausal,up to 20cm Large ovoid/irregular anechoic cyst pt w/history of PID,trauma,endmetrioses Peritoneal Inclusion cyst
Focal areas of endmetriosis, under 15cm. Cyst walls thick & fibrotic Multiple lesions w/echgenic, fluid filled content, solid, complex, cystic Endometriosis
Endometriosis means Overgrowth, outside uterus
Polycystic ovarian, Ovarian Hyperstimulation, Ovarian Remnant are all Syndromes
Chronic endoocrine disorder associated w/obesity, amenorrhea, anovulation, hirsutism & infertility. Bilateral enlargement of ovary multiple "Cortical Cyst" means (Ring of Pearls) 2-6cm(or 2-5xlarger) can still have kids w/help Polycystic ovarian syndrome "PCO"
Known as STEIN LEVENHAL Syndrome; infrequent periods can't ovulate, low levels of FSH so follice is not being stimulated PCO Polycystic ovarian syndrome
Occurs w/women undergoing ovulation induction. Occurs after FSH is given followed by hGc women w/increased risk: young thin and some w/ploycystic ovaries; will regress w/in 6wks Ovarian Hyperstimulation Syndrome (OHS)
Trying to get ovary to ovulate due to it not working. FSH stimulates follice. Done to harvest the egg for invetro Ovulation Induction
Shows cystic ovarian enlarement(>5cm)& small to moderate amount of pelvic fluid abdominal distenstion, nausea, vomiting Mild to moderate OHS
Shows systic ovarian enlargment w/abdominal distention, pain w/or w/out nausea,vomiting or diarrhea Ascites or pleural effusion can occur Severe OHS
Complication of oophorectomy. Pt w/anatomy distorted by adhesions or endometrosis. Ovary removal is difficult w/distortion & postoperative remnants of tissue become functional & you get a cystic or complex mass Ovarian Remnants Syndrome
Removal of the ovary Oophorectomy
80% of all ovarian tumors are Benign
Benign ovarian tumors are categorized as? Germ Cell Tumor Epithelial Tumor Stromal Tumor
In adults 95% are benign & consist of mature cycstic teratomas. 2nd largest group of masses. Account for 20% of neoplasms & occur in 1st-6th decades mostly women younger than 2yr Germ Cell Tumor
Mature cystic teratomas "Dermoid cysts" of the ovary ar the most common GERM cell tumor & ovarian neoplasm.Occurs in reproductive yrs. Composed of 3 germ cell layers Benign Cystic Teratoma
What ae the 3 germ layers Ectoderm, Mesoderm, & Endoderm
Pure form is always benign, 15% bilateral, varies form .5-40cm. Composed of fat,hair,teeth "Dermoid" Benign Cystic Teratoma
Sonographically appear w/ bright echos, hyperechoic lines & dots, shadowing, fluid-filled level,cystic, colid or complex Apperance of a Dermoid
60% measure 5-10 cm You can see the ecogenic portion (top) but not the botton Associated w/teratoma surgical removal in young pt, keep ovary "Tip of the Iceburg"
Benign ovarian Teratoma contaning Throid tissue. treatment is removal. 5% pt w/this develop hyperthyroidism Struma Ovari
On basis of cell type & nature of secretion most common of epithelial tumors are classified as? Serous, Mucinous,or endmetroid
Most epithelial are Adonoma or adenocarcinoma
Benign Epithelial Ovarian Tumors: Arise from ovarian epithelium Serous cystadenoma,Mucinous cystdenoma, Transitional cell tumor
25% of all benign ovarian tumors 50-70% of all ovarian serous tumors unilocular maybe bilateral Contains thin clear serouses fluid peak incidence 4th & 5th decades Serous Cystadenoma
20-25% of all benign ovarian tumors 75-85% of all ovarian mucinous tumors Multiloculated cystic tumor, onesided up to 50cm Peak 3rd to 5th decades Mucinous Cystadenoma
More papillary projections,less common, secreates mucinous yellowish Gelly like material. contained w/in tumor Mucinous
Derived form "surface epithelium" 1-2 % of all Primary ovarian tumors, less than 10cm most are 2cm 4th to 8th decades 40-80yr 96 % are primarily unilateral, hypoechic, solid,calcification may be seen Brenners Tumor "Transitional cell tumor"
Benign Stromal Ovarian Tumors: account for approximately 8% of all ovarian tumors Fibroma, Thecoma, Sertoli-Leydig tumor
Ovarian tumor accounts for 4% Seen in middle age size: very small to large Fibroid like tumor, attenuates sound (shadows) Associated w/Meig's Syndrome Fibroma
Condition in which solid benign ovarian tumor is associated w/ascites & pleural effusions Meig's Syndrome
1% of ovarian tumors 84% in postmenopausal women, can occur in young girls, 5-10 cm can be 30cm unilateralsimilar to fibroma in appearance, shadowing, can become invasive, irrgular period in young girls ESTROGEN PRODUCING TUMOR Thecoma
<0.5% of ovarian tumors all ages common in 25yr olds ANDROGEN PRODUCING UNILATERAL, 5-15cm 20% are malignant Masqulizing tumor: deep voice facial hair. Irrigular period, infertility is a sign of smaller tumors. if taken out will reoccur Sertoli-Leydig Cell tumor
Estrogen tumor, small= benign;large=malignant, 95% in postmenopausal women, 5% pt associated w/endometrial carcinoma average 12cm, 50-55yr old Adenoma slow growing Granulosa Cell Tumor
Ovarian cancer accounts for 4% in women. 4th leading cause of death in women Increased risk w/family history of ovarian or breast cancer high risk if ovulation lasts longer than 40yrs ( early period) "Malignant Ovarian Tumors"
Malignant tumor catergories Germ Cell, Epithelial, & Metastatic
60% ovarian neoplasms are Germ Cell origin, & 1/3 are malignat Germ Cell Tumor
1st Germ Cell Tumor, most common malignant childhood & early adult life. 2nd most common observed in pregnancy. 3-5% malignancies, at any age 20-30yrs bilateral in 10-17%. Solid, round or lobulated, varies in cm up to 50cm Histologically same as Seminoma Dysgerminoma
Uncommon malignant tumor 1% of all teratomas of ovary, 1st 2decades of young life, usually large up two 28cm, mostly solid but can have cystic areas Composed of all 3 embyonic layers Immature Teratoma
2nd most common malignant Germ Cell after Dysgerminoma 20-30 yrs old unilateral 3-30cm, solid w/cystic areas spread fast PT's blood will have serum increased level of ALPHAFETOPROTEIN Comes from embyonic components, can occur in testical 85% cure rat Yolk Sac Tumor
end of Germ cell tumor
Malignant epithelial tumor accounts for 90-95% of ovarianmalignancies Epithelial Ovarian Tumor
Most common primary carcinoma of ovary 40-50%. 45-65 yrs old, bilateral 50% of time. Multilocular,Multiple Papillary projections( can go thru tumor & spread) "SEEDING" & Septations, can have echogenic foci (bright). 1/2 are greater than 15 cm Serous Cystadenocarcinoma
80% are malignant 20-25% of ovarian carcinomas associated w/ endomertum Bilateral in 28% of cases 50-60yrs old 12-20 cm cystic mass w/papillary projections Endometroid Carcinoma
5-10 % malignant ovarian tumor 4th to 7th decades, 15-20% bilateral 15-30 cm, appear cystic, multiloculated, papillary projections w/echogenci material fewer papillary projection than serouses Mucinous Cystadenocarcinoma
50-70 yrs olds, bilateral in 15-20% of cases & up to 30cm. present as complex, predominantly cystic masses associated w/Endometriosis in 50-70 %of cases, 25% come from linningof endometriotic cyst Clear Cell Tumor
Mostly Benign, Maliganant Brenner's tumor larger than benign form. 10-30cm Cystic spaces & areas of hemorrhage & necrosis Transitional Cell ( BERNNER'S) Tumor
Rare, caused by metastasis of mucin producing tumor. Epithelial cells implant on peritoneum & secretes a GELATINOUS material that is not absorbed well. Resembles ascites or multiple clusters of anechoic spaces abdomin can fill up w/ mucin gelly"GELLY B PSUEDOMYXOMA PERITONEI
Primary cancer spread thru different routes, extension involves pelivc organ w/tumor. Peritoneal seeding, tumor cells shed from lesionthru lymphatic system & blood stream. Blocks the lymphatic system causes ascites. Estrogen receptor Ovarian Metastatic Dieases
Bilateral,complex cysts reflecting presence of fluid & mucin within them, solid. common primary cancer that spread to ovary:breast,gastric & intertinal Ovarian Metastatic Dieases
A Ovarian Metastatic Dieases is Ovarian Lymphoma
Ovarian Lymphoma is a Rare tumor, from the disease lymphoma elsewhere in the body. Burkitt's lymphoma affect the ovary frequently & looks like a solid hypoechoic mass
secondary tumor of ovary from GI TRACK, primary cancer ( usually stomach); bilateral Ascites maybe & complex looking KRUKENBERG TUMOR
Treatment of Ovarian cancer Surgery, Radiation therapy, & chemo. Early detection
Talcum powder has been implicated a possible factor for ovarian cancer due to? Powder travel via genital tract & acts as an irritant promoting cancer growth
Has been proven not to be successful or cost effective screening tool. Ultrasound
Created by: yovana2011
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