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Belmont PharmTest4a
Belmont Pharm test
| Drug name | Action | Side Effects | Nursing Implications |
|---|---|---|---|
| levodopa | stimulates synthesis of dopamine | NV, dyskinesias, postural hypotention, hallucinations (common), on-off phenomenon, dark sweat/urine | don't take w/ high protein food, check IOP in glaucoma pts, DM check BG, improvement w/in 2-3 weeks |
| levodopa-carbidopa | combo drug, most pts take, makes levodopa more available | abnormal movements and psych disturbances occur sooner and are more intense | none |
| Mirapex | dopamine receptor agonist | N, dizziness, daytime drowsiness, night insomnia | none |
| amantadine | rapid response but less profound for parkinson's, also antiviral | confusion, antimuscarinic, dermatologic effects | none |
| benztropine mesylate | mild symptoms in early stages of parkinson's disease | confusion, depression in elderly, anticholinergic effects in high doses, peripheral effects | withdrawl gradually |
| hydrocortisone | RA, leupus, IBD, allergies, asthma, cancer, inflammatory disorders | adrenal insufficiency, infection, PUD, F/E imbalance, osteoperosis, hyperglycemia, psyc dist, iatrogenic Cushings | give in AM w/ food, teach, don't withdraw suddenly, give more in times of stress, inc in PUD w/ NSAIDS |
| prednisone | RA, leupus, IBD, allergies, asthma, cancer, inflammatory disorders | adrenal insufficiency, infection, PUD, F/E imbalance, osteoperosis, psyc dist, iatrogenic Cushings | give in AM w/ food, teach, don't w/drawl suddenly, more in times of stress, inc in PUD w/ NSAIDS |
| dexamethasone | RA, leupus, IBD, allergies, asthma, cancer, inflammatory disorders | adreanl insufficiency, infection, PUD, F/E imbalance, osteoperosis, hyperglycemia, psyc dist, iatrogenic Cushings | give in AM w/ food, teach, don't w/drawl suddenly, give more in times of stress, inc in PUD w/ NSAIDS |
| fludrocortisone acetate | mineralocorticoid, inc reasorption of Na/Cl, excretes K | HTN, edema, cardiac enlargement, hypokalemia | monitor weight, BP, electrolytes |
| levothyroxine sodium | replaces T4 in hypothyroidism and goiter | rare: tachy, angina, tremor, insomnia, nervousness, hypothermia, heat intolerance, sweating (like hyperthyroid) | monitor response. interacts w/ cholestyramine, Ca supplements, iron |
| PTU | hyperthyroidism, before thyroidectomy, for Graves disease, w/ thyrotoxic crisis | rash (most common), N, joint pain. Rare: angranulocytosis (fever, sore throat), hypothyroidism | watch dose w/ pregnant and lactating |
| Tapazole | hyperthyroidism, before thyroidectomy, for Graves disease, w/ thyrotoxic crisis | rash (most common), N, joint pain. Rare: angranulocytosis (fever, sore throat), hypothyroidism | watch dose w/ pregnant and lactating |
| radioactive iodine 131 | hyperthyroidism | hypothyroidism | effects seen in 2-3 months |
| (CAL...-OL) | vit D supplement to treat hypocalcemia | none | none |
| calcitonin-salmon | decreases amount of calcium leaving the bones | none | none |
| (-RONATE) | inhibits bone resorption | esophagitis | don't give w/ food, only H20, sit upright after taking |
| Evista | prevents and treats osteoperosis; breast cancer | DVT, preg X, hot flashes | none |
| Genotropin | children w/ slow growth, Prayder-Willi syndrome | hyperglycemia, carpal tunnel, fataility w/ Prayder-Willi and resp disorders | none |
| (-PRESSIN) | kindeys reabsorb H2O | water intoxication, vasoconstriction, angina | none |
| (-AMIDE) | stimulates release of insulin from pancreas | hypoglycemia, weight gain, profuse sweating, weakness | interacts w/ NSAIDS, sulfonomides, alcohol, d/c 24-72h before surgery and give insulin coverage |
| (GL...-IDE) | stimulates release of insulin from pancreas | hypoglycemia, weight gain, profuse sweating, weakness | interacts w/ NSAIDS, sulfonomides, alcohol, d/c 24-72h before surgery and give insulin coverage |
| Glucophage | DM2 treatment and prevention, decreases liver prod of glucose | anorexia, metallic tate, ND, dec folic acid and B12, lactic acidosis | don't give to pts with renal, hepatic or CV disease |
| Prandin | DM2, stimulates insulin release | hypoglycemia | none |
| Acarbose | DM2, delays absorption of CHO | GI discomfort, liver dysfunction w/ long term use, no hypoglycemia | take w/ 1st bite of meal, CHO are 40% of meal, 25-100mg |
| (-GLITAZONE) | dec insulin resistance, in resonse to insulin, dec glucose production from liver | expands blood volume, may raise lipid levels, no hypoglycemia | monitor lipids, LFTs, heart, I&O |
| Symlin | DM 1&2, delays gastric emptying, decreases post prandial glucose | hypoglycemia, N, injection site reactions | Peak=20min, delyas absorption of PO drugs, so take them 1h before or 2h after |
| Byetta | DM2, slows gastric emptying, stimulates insulin release, suppresses appetite | hypoglycemia, NVD, anti-exenatide antibodies | Peak=2h, delays PO drugs, 1h before or 2h after |