Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

PCSOM Block 4

Drug Classes/Drugs/MOAs

Drug ClassDrugMech of Action
Natural Penicillins Penicillin G Cell Wall Inhibitor, Beta-Lactam antibiotic
Natural Penicillins Penicillin V Cell Wall Inhibitor, Beta-Lactam antibiotic
Antistaph Penicillins Methicillin Cell Wall Inhibitor, Beta-Lactam antibiotic
Antistaph Penicillins Nafcillin Cell Wall Inhibitor, Beta-Lactam antibiotic
Amino Penicillins Ampicillin Cell Wall Inhibitor, Beta-Lactam antibiotic
Amino Penicillins Amoxicillin Cell Wall Inhibitor, Beta-Lactam antibiotic
Antipseudomonal Penicillins Piperacillin Cell Wall Inhibitor, Beta-Lactam antibiotic
Antipseudomonal Penicillins Carbenicillin Cell Wall Inhibitor, Beta-Lactam antibiotic
Antipseudomonal Penicillins Ticarcillin Cell Wall Inhibitor, Beta-Lactam antibiotic
Antipseudomonal Penicillins Mezlocillin Cell Wall Inhibitor, Beta-Lactam antibiotic
1st Gen Ceph cefazolin Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
1st Gen Ceph Cephalexin Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
2nd Gen Ceph Cefaclor Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
2nd Gen Ceph Cefoxitin Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
2nd Gen Ceph Cefuroxime Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
2nd Gen Ceph Cefamandole Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
3rd Gen Ceph Cefoperazone Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
3rd Gen Ceph Cefotaxime Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
3rd Gen Ceph Ceftazidime Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
3rd Gen Geph Ceftriaxone Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
4th Gen Ceph Cefepime Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
Carbapenems Imipenem Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
Carbapenems Meropenem Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
Carbapenems Ertapenem Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
Monobactams Aztreonam Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
Other: Affecting Cell Wall Vancomycin Glycopeptide inhibits cell wall synthesis by preventing peptidoglycan elongation; bactericidal; bacteriostatic for enterococci
Other: Affecting Cell Wall Teicoplanin (blank)
Other: Affecting Cell Wall Bacitracin (blank)
Other: Affecting Cell Wall Polymyxin (blank)
Tetracyclines Tetracycline Bacteriostatic; Blocks protein synthesis by binding to 30S ribosomal subunit & blocking access of amino acyl-tRNA to mRNA ribosome complex at acceptor site. Prevents addition of amino acids to growing peptide.
Tetracyclines Doxycycline Bacteriostatic; Blocks protein synthesis by binding to 30S ribosomal subunit & blocking access of amino acyl-tRNA to mRNA ribosome complex at acceptor site. Prevents addition of amino acids to growing peptide.
Aminoglycosides Gentamicin (prototype) Bactericidal; Entry of drugs into bacterial cells; Blocks Protein synthesis at 30S
Aminoglycosides Amikacin Bactericidal; Entry of drugs into bacterial cells; Blocks Protein synthesis at 30S
Aminoglycosides Streptomycin Bactericidal; Entry of drugs into bacterial cells; Blocks Protein synthesis at 30S
Macrolides Erythromycin Bacteriostatic; Blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
Macrolides Clarithromycin Bacteriostatic; Blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
Macrolides Azithromycin Bacteriostatic; Blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
Other Protein Synthesis Inhibitors Chloramphenicol Binds to 50S and inhibits peptidyl transferase step of protein synthesis
Other Protein Synthesis Inhibitors Clindamycin Binds to 50S and inhibits peptidyl transferase step of protein synthesis
Other Protein Synthesis Inhibitors Streptogramins (quinupristin & dalfopristin) Bacteriostatic; blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
Other Protein Synthesis Inhibitors Linezolid Bacteriostatic; blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
Other Protein Synthesis Inhibitors Telithromycin Bacteriostatic; blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn - binds 10x tighter
Other Metronidazole Metabolized to active form by ferredoxin that inhibits DNA
Other Daptomycin Binds to cell membrane causing rapid depolarization; loss of membrane potential inhibits protein, DNA & RNA synthesis
Sulfonamides Sulfacetamide Bacteriostatis; Competes with PABA for dihydropteroate synthase & prevents synthesis of folic acid
Sulfonamides Silver Sulfadiazine Bacteriostatis; Competes with PABA for dihydropteroate synthase & prevents synthesis of folic acid
Sulfonamides Trimethoprim-Sulfamethoxazole inhibits dihydrofolate reductase blocking purine, pyrimidine & amono acid synthesis - synergistic preventing of formation of tetrahydrofolic acid
Fluoroquinolones Norfloxacin Inhibition of topoisomerase II
Fluoroquinolones Ciprofloxacin Inhibition of topoisomerase II
Fluoroquinolones Ofloxacin Inhibition of topoisomerase II
Fluoroquinolones Gatifloxacin Inhibition of topoisomerase II
Fluoroquinolones Levofloxacin Inhibition of topoisomerase II
Fluoroquinolones Moxifloxacin Inhibition of topoisomerase II
Fluoroquinolones Sparfloxacin Inhibition of topoisomerase II
Urinary Tract Antiseptic Nitrofurantoin Metabolized to active form by the bacteria inhibiting various enzymes & damages DNA
Antigout Agent Probenecid Inhibits tubular reabsorption of uric acid increasing the urinary excretion of uric acid
Created by: spurrp
Popular Pharmacology sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards