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RCP113 U4 Q&A
C18/21/22 Muscle Relaxants/CNS drugs/Diuretic agents
| Question | Answer |
|---|---|
| NMBAs or Neuromuscular Blocking Agents are also called? | Paralytics or Muscle relaxants |
| What are the primary (4)clinical uses for NMBAs? | Intubation Surgery Enhance CO2 removal-ventilator sychronicity Reduce intercranial pressure (ICP) |
| What neurotransmitter is effect by NMBAs? | Acetylcholine (ACh) |
| NMBAs are divided into 2 types, what are they? | Depolarizing and Nondepolarizing |
| What is the only depolarizing agent now available? | Succinylcholine |
| What enzyme inactivates Acetylcholine (ACh)? | Acetlycholinesterase (AChE) |
| What is the function of acetylcholine in the nervous system? | Transmission of nerve impulses |
| Uncoordinated muscle contractions caused by some NMBAs are called? | Fasciculations |
| What is considered an ideal NMBA for intubation and why? | Succinylcholine (depolarizing agent) because of its quick onset (60-90sec) and its short duration (10-15min) |
| T/F? A conscious Pt who receives skeletal muscle relaxants (NMBA) can still feel pain. | True-It is always required to administer a sedative prior to paralyzing (use of NMBA) |
| T/F? Use of skeletal muscle relaxants (NMBA) results in complete apnea | True-Pt has inadequate ventilation/oxygenation and is probably hypercapnic/hypoxemic |
| What are nondepolarizing NMBAs used for? | Maintenance of Pts on invasive mechanical ventilation |
| What are the potential side effects of a depolarizing agent? | Decreased B/P Bradycardia Increased K+ Muscle soreness Histamine release |
| What are some of the uses fro non-depolarizing NMBAs? | Mechanical ventilation Status ashmatics ARDS Trauma |
| How can non-depolarizing NMBAs be reversed? | Make more ACh available by using aceytlcholinesterase inhibitors |
| A Pt using Lithium should indicate what? | He/she has BiPolar disorder. |
| Which type of sedative/tranquilizer is most effective? | Benzodiazepine are most effective. |
| What is another name for narcotic agents? | Opiates |
| What drug is used to antagonize the effects of opiates? | Naloxone (Narcan) |