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pharmacologytest#2

QuestionAnswer
Bethanechol is a choline ester used for Cholinergic agonist | postpartum and postoperative nonobstructive urinary retention
Carbachol is a choline ester used for Cholinergic agonist | Miotic agent Opthalmic solultion tx of glaucoma
Pilocarpine is a natural alkaloid used for Cholinergic agonist | opthalmic agent in tx of glaucoma
Name two prototype Muscarinic Blockers Atropine Scopolamine
Cycloplegia would cause parlysis of the ciliary muscles
Iproptropium Muscarinic Blocker | bronchodilation
Tiotropium Muscarinic Blocker | COPD
Methscopolamine bromide Muscarinic blocker | GI spasms
Homatropin Methylbromide Muscarinic blocker | GI spasms, irritable bowel
Prothantheline Muscarinic blocker | Ulcer
Glycopyrrolate anti-vagal drug with general anesthesia
Pirenzepine Muscarinic blocker | M1,M4 selective | Acid-peptic disorders
Darifenacin(Enablex) Muscarinic blocker | M3 selective | urinary and fecal incontinence
Oxybutinin(Diprovan) Muscarinic blcoker | Anti-spasmodic
Echothiophate(Phospholine Iodide) Indirect cholinergic agonists | Muscarinic | Glaucoma
Diisopropylfluorophosphate(DFP) Indirect cholinergic agonists | Muscarinic | Glaucoma
Neostigmine(Prostigmin) Indirect cholinergic agonist | Nicotinic | Myasthenia Gravis
Ambenonium(Mytelase) Indirect cholinergic agonist | Nicotinic | Myasthenia Gravis
Pyridostigmine(Mestinon or Regonol) Indirect cholinergic agonist | Nicotinic | Myasthenia Gravis
This drug is used for the diagnosis of Myasthenia Gravis or differentiation of Cholinergic Crisis Edrophonium(Tensilon)
Physostigmine(Antilirium) Indirect Cholinergic Agonist | Cognitive disorders of Alzheimer's
Tacrine(Cognex) Indirect Cholinergic Agonist | Cognitive disorders of Alzheimer's
Donepezil(Aricept) Indirect Cholinergic Agonist | Cognitive disorders of Alzheimer's
Galantamine(Reminyl) Indirect Cholinergic Agonist | Cognitive disorders of Alzheimer's
Beta-1 effect Heart inotropic,chronotropic,dromotropic
Beta-1 effect Kindey Juxtaglomerular cells renin release
Beta-2 effect Blood vessels dilate-oppose alpha1
Beta-2 effect Bronchioles dilate
Beta-2 effect Uterus relax
Beta-2 effect Liver glycogenolysis
Beta-2 effect Pancreas mild insulin stimulation
Beta-2 effect Skeletal mm increase contractility
Beta-2 effect Eye relax ciliary mm for far vision
Alpha-1 effect Most vascular smooth muscle Contraction
Alpha-1 effect Pupillary dilator muscle Contraction
Alpha-1 effect Pilomotor Erects hair
Alpha-1 effect Prostate Contraction
Alpha-2 effect Postsynaptic CNS adrenoceptors Probably multiple
Alpha-2 effect Platelets Aggregation
Alpha-2 effect Adrenergic and cholinergic nerve terminals Inhibition of transmitter release
Alpha-2 effect Some vascular smooth muscle Contraction
Alpha-2 effect Fat cells Inhibition of lipolysis
Norepinephrine DAA a1: vasoconstriction b1: + inotropic, chronotropic, dromotropic
Epinephrine DAA low dose (beta), high dose(alpha) a1: vasoconstriction b1: + inotropic, chronotropic, dromotropic b2: bronchodilation, skel. m. & other vasc. dilation
Dopamine DAA b1: stimulatory activity on heart improves renal blood flow
Isoproterenol DAA b1: + inotropic, chronotropic, dromotropic b2: bronchodilation, vasodilation
Dobutamine Beta-1 Agonist + inotropic
Albuterol Beta-2 Agonist Short acting
Terbutaline Beta-2 Agonist Short acting
Salmeterol Beta-2 Agonist long acting
Formoterol Beta-2 Agonist long acting
Ritodrine Beta-2 Agonist tocolytic
Beta-2 Agonist adverse effects Cardiac arrhythmia, -K+ , +BG, some b1 activity
Pseudophedrine Alpha-1 agonist nasal decongestant
Phenylephrine Alpha-1 agonist mydriasis
Oxymetazoline Alpha-1 agonist nasal decongestant
Tetrahydrozaline Alpha-1 agonist red out by vasoconstriction
Methoxamine Alpha-1 agonist treat hypotension states
Mephenteramine Alpha-1 agonist used to treat hypotension Direct and indirect
Metaraminol Alpha-1 agonist | paroxysmal supraventricular tach
Midodrine Alpha-1 agonist | treatment of autonomic insufficiences and postural hypotension
Levophed (NE) Alpha-1 agonists | treatment of severe acute hypotension | shock
dexamphetamine weight reduction
benzamphetamine weight reduction
phentermine weight reduction
Phendimetrazine weight reduction
Phenmetrazine weight reduction
Phenylpropanolamine used to be in weight reduction group
Tizanidine Alpha-2 agonist | muscle relaxant
Brimonidine Alpha-2 agonist | anti-glaucoma agent (decreases aqueous production and increases outflow)
Phenoxybenzamine Alpha-1 antagonists | (a1>a2)noncompetitive | treatment of pheochromocytoma | decreass systolic and diastolic
Phentolamine Alpha-1 Antagonists | (a1=a2)competitive | treatment of pheochromocytoma |
Prazosin Alpha-1 Antagonist | (a1>>>a2)competitive | hypertension
Doxazosin Alpha-1 Antagonist | (a1>>>a2)competitive | hypertension and BPH
Terazosin Alpha-1 Antagonist | (a1>>>a2)competitive | hypertension and BPH
Tamsulosin Alpha-1 Antagonist | (a1>>>a2)competitive | BPH
Yohimbine Alpha-2 Antagonist | Erectogenic, stimulates libido
Propanolol Beta blocker (b1&b2)
Pindolol Beta blocker ISA
Metoprolol Beta blocker (b and a1)
Yohimbine Alpha-2 Antagonist | Erectogenic, stimulates libido
Propanolol Beta blocker (b1&b2)
Pindolol Beta blocker ISA
Metoprolol Beta blocker (b and a1)
Tolerodine(Detrol) Muscarinic blocker | anti-spasmodic
CNS targeted Muscarinic blockers Benztropine, Trihexyphenidyl, Biperiden, Procyclidine (Anti-Parkinson's)
Created by: 1665548338
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