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Pharm-Chap20 Immuno
| Question | Answer |
|---|---|
| carboplatin | Paraplatin |
| cisplatin | Platinol |
| cyclophosphamide | Cytoxan |
| dactinomycin/actinomycin D | Cosmegen |
| doxorubicin | Adriamycin |
| androgens | danazol (Danocrine) |
| estrogens | ECP/Synovex C |
| Glucocorticoids | Pred/Dex |
| azathioprine | Imuran |
| hydroxyurea | Hydrea/Droxia |
| vinblastine | Alkaban-AQ/Velbane |
| vincristine | Oncovin/Vincasar |
| filgrastin | Neupogen |
| Sargramostine | Leukine |
| Interleukin-2 | Proleukin |
| acemannan | Acemannan Immunostimulant |
| cyclosporine | Optimmune-Opthalmic ointment/Sandimmune-Oral/Atopica-Injection |
| azathioprine | Imuran-Tabs & Injection |
| cyclophosphamide | Cytoxan |
| mercaptopurine | Purinethol |
| l-asparaginase | Elspar/Oncaspar |
| toceranib | Palladia-Oral tab |
| Antineoplastic Drugs | AKA - anticancer drugs & chemotherapeutic agents |
| G1 phase | Enzyme production |
| G2 phase | RNA & protein synthesis |
| S phase | DNA synthesis & replication |
| M phase | mitosis |
| G0 phase | resting phase |
| CCNS | work during any phase |
| CCS | work during specific phase |
| Growth fraction | % of cancerous cells actively dividing |
| Doubling time | time required for number of cancerous cells to double |
| Pulse dosing | method of delivering chemo agents to produce increased levels of drug early & then prolonged dose-free period |
| CCNS-Alkylating agents | carboplatin/cisplatin/cyclophosphamide |
| CCNS-Antitumor antibiotics | dactinomycin/actinomycin D/doxorubicin |
| CCNS-Steroid drugs | androgens/estrogens/glucocorticoids |
| CCS-Antimetabolites | azathioprine/hydroxyurea |
| CCS-Alkaloids | vinblastine/vincristine |
| Immune Enhancers | Roferon-A Injection/Intron-A Injection |
| CSFs | filgrastin/sargramostine |
| Interleukins | interleukin-2 |
| Immune Dehancers | cyclosporine/azathioprine/cyclophosphamide/mercaptopurine |
| Enzymes | l-asparaginase |
| Enzyme Inhibitors | toceranib |
| Sarcoma | cancer of connective tissue |
| Leukemia | cancer of WBCs |
| Tyrosine Kinase | enzyme from some tumors that inhibits & kills off cells |
| All phases | CCNS |
| CCS-Antimetabolites | S phase |
| CCS-Alkaloids | M phase |