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IOS 11 Exam 1
Parasitic Diseases
| Question | Answer |
|---|---|
| Symposis is | Two species living together |
| Commensalism is | Relationship between two kinds of organisms in which one obtains food or other benefits from the other without damaging or benefiting it |
| Parasitism is | Host species is harmed throught the activitis of the other |
| Malaria pathogens | Protoza-Plasmodium malariaw, P. vivas, P. faliciparum, P.ovale attack mosquito then anapheles mosquito attaches human via bite |
| s/s of malaria | Fever, anemia, thrombocytopenia, ARF, vascular damage |
| Treatment of malaria | Chloroquine, Quinidine (later presentation) or Mefloquine |
| Chloroquine SE | N/V, diarrhea, GI, pruritis, HA, visual disturbances, confusion, fatigue |
| Quinidine SE | QT prolongation, Cinchinism (flush, sweaty, HA, vertigo) |
| Leishmaniasis pathogens | L.braziliensis, L.mexicana transmission via ingestion into dog, squirrel and mosquito bites and then human gets a bite |
| Leishmaniasis presntation | Can be viseral stomach, cutaneous skin lesions or Mucocutaneous |
| Treatment of leishmaniasis | Stilbogluconate sodium from the CDC (intergeres with glycolysis, FA oxidation ion glycosomes) |
| SE of Stibogluconate sodium | Injection site reaction, muscle pain, thrmbocytopenia |
| Entamoeba Histolytica pathogen | A one cell amoeba that lives in the colon and can cause lesions and necrosis |
| Treatment of entamoeba histolytica | Paromomycin, lodoquinol, Diloxanide furoate. If Systemic- Metronidazole, tetracycline, chlorquine |
| Giardia Lamblia characteristics | Most common intestinal disorder protoza is from contaminated water of food |
| Treatment of Girdia Lamblia | metronidazole 250mg TID 7 days |
| Protozan infections are | Malaria, Leishmaniasis, Entamoeba histlytica, Giardia |
| Helminthes infections are | Necator americanus (hook), Ascariasis (round worm), Enterobiasis (round pinworm) |
| Necator americanus characteristics | Found more in the southeastern US- via contiminated food or skin penetration Treat with Mebendazole 100mg PO BID x3 days |
| Ascariasis (roundworm) | Found in the gulf coast states and Appalachian Females are 20-35cm can migriate to lungs Treatment with Mebendasole 100mg PO BID x 3 |
| Mebendazole MOA | Inhibits tubulin synthesis this inhibits glucose uptake and larval development |
| Enterobiasis (round pinworm) Characteristics | Most common & in children affected perianal can test with scotch tape Treated with Pryrantel pamoate, mebendazole, Abendazole |
| Pyrantel pamoate MOA | Neuromuscular blocker |
| Prophylatic treatment to prevent malaria is | DEET spray, Chlorquine, mefloquibe, doxycycline, Atovaquone + proguanile |