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PHARM35
drugs for bacterial infection
| Question | Answer |
|---|---|
| pathogens | organisms that can cause disease |
| Pathogens must bypass the body's defenses: two ways: | invasiveness and toxin production |
| pathogens that divide rapidly to overcome and cause direct damage: invading | invasiveness |
| pathogens that are very small amounts disrupt normal cell function: one viral cell | toxin production |
| pathogens | organisms that can cause disease |
| ability of an organism to cause infection: cold virus- disruption | pathgenicity |
| Pathogens must bypass the body's defenses: two ways: | invasiveness and toxin production |
| Anti- infective drugs are known as | antibacterial, antimicrobal, antibiotic |
| pathogens that divide rapidly to overcome and cause direct damage: invading | invasiveness |
| Anti- infective drugs: pharmacological class | mechanism of action ( cell wall inhibior, folic- acid inhibitor) |
| pathogens that are very small amounts disrupt normal cell function: one viral cell | toxin production |
| Anti- infective drug: Therapeutic class | anitbacterial, antimicrobial, antibiotic |
| ability of an organism to cause infection: cold virus- disruption | pathgenicity |
| action of anti- infective drugs | affect target organim's structure, metabolism, or life cycle |
| ability of a microbe to produce disease when present in minute numbers: | virulence |
| goal of anti- infected drugs is to eliminate | pathogen |
| Anti- infective drugs are known as | antibacterial, antimicrobal, antibiotic |
| kill bacteria | bactericidal |
| Anti- infective drugs: pharmacological class | mechanism of action ( cell wall inhibior, folic- acid inhibitor) |
| slow growth of bacteria | bacteriostatic |
| Anti- infective drug: Therapeutic class | anitbacterial, antimicrobial, antibiotic |
| Antituberculosis drugs used to prevent disease in high- risk populations | chemoprophylaxix |
| action of anti- infective drugs | affect target organim's structure, metabolism, or life cycle |
| Close contacts and family members of recent | |
| goal of anti- infected drugs is to eliminate | pathogen |
| kill bacteria | bactericidal |
| slow growth of bacteria | bacteriostatic |
| Antituberculosis drugs used to prevent disease in high- risk populations | chemoprophylaxis |
| drug given to Close contacts and family members of recently infected TB clients | chemoprophylaxis |
| drug given to clients with AIDS | chemoprophylaxis |
| drug given to clients who are HIV- positive or are recieving immunosuppresant drugs | chemoprophylaxis |
| prototype for Penicillin | penicillin G (pentids) |
| Penicillin's mechanism of action | kill bacteria by disrupting their cell walls |
| Penicillin's primary use: | as a drug of choice against streptococci, pneumococci, and staphylococci organisms that do not produce penicillinase |
| Penicillin G (pentids) is also a med of choice for | gonorrhea and pyphillis |
| Adverse reactions for penicillin G(pentids) | diarrhea, nausea, vomiting, superinfections, anaphylaxis |
| Prototype drug for Cephalosporins | cefotaxmine (claforan) |
| cefotaxmine (claforan) mechanism of action | to act with broad spectrum activity against gram- negitive organisms |
| cefotaxmine (claforan) primary use: | for serious infections of lower respiratory tract, CNS, genitourinary system, bones, blood and joitns |
| Adverse affects of cefotaxmine (claforan) | hypersenitivty, anaphylaxis, diarrhea, vomitting, nausea, pain at injection site |
| Tetracycline prototye drug: | tetracycline HCL (Achromycin, others) |
| tetracycline HCL mechanisms of action: | effective against broad range of gram + and gram - organisms |
| Primary use of Tetracycline HCL (Archomysin) | clamydiae, rickettsiae, and mycoplasm |
| Adverse affects of Tetracline HCL (Archomysin) | superinfections, nausea, vomitting, diarrhea, discoloration of teeth, photosensitivity |
| Macrolide prototype drug: | erthromysin (E- Mysin, Erythrocin) |
| Mechanism of action erthryomysin (E- mysin, Erythrocin) | to act as spectrum similar to that of penicillins; also effectve against gram + bacteria |
| Primary use of Erythromysin (E- mysin, Erythrocin) | Bordetella pertusis (whooping cough) and Corynebactrium diphtheriae, most gram + bacteria |
| adverse a |
Created by:
Mollie28
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