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IOS 10 exam 4
Surgical site infections
| Question | Answer |
|---|---|
| Endocarditis-Antimicrobial Prophylaxis Endocarditis-Dental | -Amoxicillin 2 g or PCN clindamycin, cephalexin, cefadroxil, azithromycin, clarithroymycin |
| GU/GI- High risk-treatment | High risk- Ampicillin 2g + gentamycin 1.5mg/kg or Vancomycin 1g + Gentamicin 1.5mg/kg Moderate- Amoxicillin 2 g or Vancomycin 1 g |
| High-Risk patients | Prosthetic valves, Previous bacterial endocarditis, Cyanotic congenital heart disease, 4. Systemic pulmonary shunts or conduits |
| Moderate-Risk patients | 1. Valvular dysfunction (e.g. rheumatic heart disease)2. Hypertrophic cardiomyopathy3. Mitral valve prolapse with regurgitation |
| Dental Prodedures (High risk & moderate risk) | Prophylaxis recommended Dental extractions Periodontal procedures (root planting) Dental implant placement, Root canal Orthodontic band placement Local anesthetic injections Teeth cleaning where bleeding is anticipated |
| Surgical prophylaxis (high Moderate risk) | -30 minutes prior to procedure, maintain 2 half-life’s except CABG, joint replacement (24-48hr) |
| No prophylaxis | Clean surgery.Exceptions-Implantation of prosthetic material, Significant morbidity associated with infection (CABG, Neurosurgery, Vascular) |
| Surgery DOC prophylaxis | DOC-Cefazolin PCN ALL-Gentamicin +- clindamycin or metronadizole or Levofloxacin + metronidazole MRSA-Vancomycin |
| Surgery (anaerobes) Apendectomy, colorectal, hysterectomy | Cefotetan or Cefoxitin |
| Intra-abdominalSurgery DOC | Cefoxitin, Neomycin Sulfate, Erythromycin, mechaniscal cleaning (mannitol, PEG, fleets phoso-soda). |
| Topical treatments | Nasal- Mupirocin, Skin-chlorhexidine (MRSA |
| Potential Micorobes | Staph, aureus, Coag (-) staph, enterococcus spp, E. coli, Pseudomonas |
| Surgical Wound Classification | 1. Clean-No acute inflammation 2. Clean-contaminated -Controlled opening of GI, respiratory, biliary, or GU tract 3. Contaminated -Penetrating trauma (<4 hours old),4. Dirty-Penetrating trauma (>4 hours old), |
| Surgery Pathogens | (Gram+ staph aureus) or intra-abdominal-E. coli, gram(-), Enteroccus, B. fragilis or Nasal- S. aureus |