click below
click below
Normal Size Small Size show me how
IOS 9 Exam 2
Urinary Incontinence/BPH
| Question | Answer |
|---|---|
| Risk foctors for Uninary Incontinence | Immobility, Gender (female), parity (childbirth), UTI, Menopause, GU surgery, lack of pastpartum exercise, various medications |
| Clinical, Psychological, and social impact of Urinary Incontinence | Rashes, pressure sores, skin&UTi's, ordor, restricted activities, embarrassment, isolation, depression, sexual dysfunctio, institutionalation |
| Stress Incontinence cause | Dysfunction of the urethral spincter leading to loss when intra-abdominal pressure increases |
| Stress Incontinence S/S | Pressure cause release-coughing, sneezing, bending, lifting, and less common at night since muscle are relaxed and no pressure exerted |
| Detrusor Instability/OVeractive bladder and Urge Incontinence cause | CNS dysregulation such as stroke, Parkinsons disease, alzehimers disease-No warning |
| Detrusor Instability/OVeractive Bladder and Urge Incontinence S/S | No warning Voiding-No characteristic features on PE, s/s -Nocturia, frequent small volume voiding |
| Overflow Incontinence causes | Bladder outlet is obstructed, spinal cord lesions, Diabetic neuropathy, muscle relaxants, calcium channel blockers, anticholinergics |
| Overflow Incontinence S/S | Palpable and percussable bladder, that is tender. Low flow rates, and post-void residual volume |
| Functional Incontinence cause | Musculoskeleta limitations, unfamilular setting |
| Iatrogenic Incontinence cause | Drugs: diuretics, hypnotics, muscle relaxants, alpha 1 agonist (pseudoephedrine), alpha antagonsts (terazosin, prazosin), anticholinergics, calcium channel blockers |
| Treatment of Detrusor instability | Anticholinergis decrease detrusor contractions, and increase bladder capacity to decrease urgency. Darifenacin, Solifenacin, Tropium, Tolterodine, Tolterodine LA, Oxybutin (pathch and XL and generic) |
| Side effects of anticholingergics | Dry mouth, constipation, cognitive impairment |
| Treatment of Stress Incontinence | Kegel exercises, topical estrogens/estring for atrophic vaginitis, pseudoephedrine, or duloxetine will all help to increase resistance to sudden intra-abdominal pressure |
| Treatment of Overflow incontinence | Improve drainage of bladder by giving: alpha antagonist (prazosin, terazosin,doxazosin, phenoxybenzamine, bethanechol) or 5 alpha reductase inhibitor (Proscar, avodart) |
| Side effects of duloxetine | HA, fatigue, insomnia, constipation, dry mouth, dizziness, increased BP |
| Side effects of alpha antagonists | Hypotension, tachycardia, impotence |
| Treatment for Functional Incontinence | Remove underlying cause, get bedside commode, schedule bathroom visits, remove sedatives |
| When behavioral interventions are used in combination with medication therapies | Excellent results. Medications alone have been shown to be minor benefit especially in nursing home patients |
| What is the role of alpha antagonists in Overflow incontinence- bladder obstruction | alpha 1 receptors inhibit the contraction of prostatic smooth muscle thus relieve bladder obstruction. |
| Contraindications of alpha antagonist | Pregnancy, blood donation for 6 months |
| What is the role of 5 alpha reductase inhibitors in bladder obstruction | Finasteride and dutasteride reduce DHT levels thus reduce the size of the prostate. Useful in men with enlarged prostrates requires 3-6 months but no change in urine flow and less symptom relief than alpha-blockers |
| AUA symptoms Index for Mild | 0-7 |
| AUA symptoms Index for Moderate | 8-19 |
| AUA symptoms Index for severe | 20-35 |
| Combination therapy for overflow incontinence when patient has | Alpha antagonist & 5 alpha reductase inhibitor if: Lower urinary tract symptoms and enlarged prostrate |
| Symptoms improvement from alpha antagonist should occur | days to weeks |
| Pharmacological selectivity of an alpha antagonsit means | No BP effects and selectivly inhibits alpha 1 |
| Functional selectivity of a alpha antagonsit means | Low peripheral BP effects although it is designed as a alpha 1 |
| No uroselectivity means | Have BP effects=terazosin and doxazosin |
| Extended release formulations of alpha antagonists | Alfuzosin, and Tamsulosin |
| Monitoring paramenters for overflow incontience | BP, volume, orthostatic hypotension |
| Psuedoephedrine not recommended for Stress incontinence patients who have | HTN |
| Drugs that cause stress incontinence | terazosin, prazosin, anticholinergics, muscle relaxants |