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Pathology F10

Signs and Symptoms of CNS Involvement

QuestionAnswer
Patterns of Muscular Weakness -upper motor neuron (spinal cord injury) -lower motor neuron (peripheral nerves) -muscle disease (ex: muscular dystrophy) -neuromuscular junction (myosina gravis) -functional
Upper Motor Neuron lesion -increased tone -hyperreflexia (increased reflexes= anything over 2+) -pyramidal pattern of weakness -weak ext in the arms -weak flex in the legs
Upper Motor Neuron Lesion Positive Signs (things that appear) -abnormal postures (synergies aren't abnormal but are different) -exaggerated proprioceptive reflexes -abnormal cutaneous reflexes -Babinski is present (extend & spreading of toes)
Upper Motor Neuron Lesion Negative Signs (things that are lost) -neurogenic shock -loss of ability to generate forse -loss of coordination, balance, and manual dexterity
Lower Motor Neuron lesion -wasting away of muscles -fasiculation (twitchy mm) -flaccid paralysis (no tone -decreaased tone (if partial innerv of a muscle is gone) -absent DTR's (cutaneous reflexes)
Examples of LMN lesions -GBS (ascending polyneuropathy -polio (attacks ant horn cells randomly) -bells palsy (LMN of the face) -carpal tunnel
Created by: CWestrick