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Heiman.pharm.vasev9

Dipyridamole

QuestionAnswer
Mechanism Causes an increase in adenosine levels producing vasodilation Inhibition of phosphodiesterase which decrease levels of cAMP Low cAMP is associated with decreased platelet adhesion
Kinetics Bioavailability 33 – 67 % Liver metabolism, CYP450 Renal Excretion
Adverse Effects Bleeding Hypotension Dizziness Nausea Flushing Rash
Cautions Use with caution when taking other blood thinners
Names Persantine Oral IV Used for exercise tolerance testing Aggrenox Sustained release in combination with aspirin
Created by: DianaB
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