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Heiman.pharm.vascev8
Aspirin
| Question | Answer |
|---|---|
| Mechanism | Inhibition of cyclo – oxygenase in platelets and endothelial cells preventing the synthesis of thromboxane A2 Potent platelet aggregator and vasoconstrictor Inhibition is irreversible Last for the life of the platelet (7 – 10 days) |
| Adverse Effects | GI upset Enteric coating may help Thrombocytopenia Bleeding |
| Cautions | Use cautiously in someone on other blood thinners |
| Names | Names Enteric coated – Ecotrin |