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Sedatives
| Question | Answer |
|---|---|
| BZD Antagonist | Flemazenil |
| BZD MOA | Depress neuron func at CNS |
| BZD AE | HYPOTENSION, CARDIAC ARREST, CNS DEPRESSION. RESPIRATORY DEPRESSION |
| BZD INTER | CNS Depressants |
| BZD Like MOA | Act on GABA but structure is different |
| BZD Like INTER | 3A4 |
| Which is the first line for insomnia | BZD Like Zolpidem |
| Esxopicolon | Bitter aftertaste |
| BZD Like Other | Avoid with high fat meals |
| Ramelteon MOA | Activation of receptors for melatonin (RAMEL => Camels like to be in the sun) |
| Ramelteon AE | Can INCREASE PROLACTIN and DECREASE TESTOSTERONE |
| Ramelteon Other | Avoid with high fat meals |
| Trazodone | |
| Tranzdone Other | Not a controlled substance |
| Doxepine | TCA Antidepressant |
| Barbituates MOA | Binds to GABA. No CEILING |
| Barbiturates AE | CNS DEPRESSION, HYPOTENSION, RESPIRATORY DEPRESSION (everything BZD but more) |
| Barbiturates INTER | CNS Depressants |
| Barbiturates OTHER | Tolerance in many |