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Pain

QuestionAnswer
ASA MOA NONSELECTIVE irreversible inhibitor of cox1
ASA AE GI, REYE'S SYNDROME, FLUID RETENTION, bleeding, renal impairment, hypersensitivity reaction
ASA INTER EtOH, GLUCOCORTICOIDS, ACE/ARBS. LITHIUM. Drugs that promote bleeding
ASA Other Avoid with asthma
NSAIDS MOA REVERSIBLE inhibition of COX1 and COX 2
NSAIDS AE GI, HYPERSENSITIVITY REACTION, REYE'S SYNDROME, FLUID RETENTION, PROLONGS BLEEDING TIMES
NSAIDS INTER DRUGS THAT PROLONG BLEEDING TIME, EtOH, glucocorticoids, ACE/ARBS, lithium
Celecoxib MOA Selective inhibition of COX 2
Celecoxib AE MI, STROKE, Sulfonamide allergy, FLUID RETENTION
Celecoxib INTER WARFARIN, EtOH, glucocorticoids, ACE/ARBs, LITHIUM
Celecoxib OTHER Does not inhibit platelet aggregation or Bleeding
Celecoxib Preg X
Acetaminophen MOA inhibits prostaglandin synthesis at the CNS
Acetaminophen AE HEPATOTOXICITY, HEPATIC NECROSIS
Acetaminophen INTER WARFARIN, EtOH
Hepatic Necrosis antidote Actylcysteine
Morphine MOA mimics actions of endogenous opioid peptides
Morphine AE RESPIRATORY DEPRESSION, ELEVATIONS OF INTRACRANIAL PRESSURE, NEUROTOXICITY, constipation, withdrawal
Morphine INTER CNS DEPRESSANTS, ANTICHOLINERGIC DRUGS, ANTIHISTAMINE, MAOIS, LINEZOLID
Treat Opioid antagonist overdose Naloxone
Drug for respiratory depression Narcain
Naltrexone Morphine. black box warning NEPHROTOXICITY
Fentanyl Morphine. Short half life
Tapentoadol MOA Central opiod agonist. inhibit NE reuptakde
Tapentoadol AE RESPIRATORY DEPRESSION, ELEVATION OF INTRACRANIAL PRESSURE. NEUROTOXICITY. SEROTONIN SYNDROME. STEVEN JOHNSON SYNDROME
Tapentoadol CNS depressants, MAOI, LInezolid, TCA, SSRI/SNRI
Created by: jyche
Popular Pharmacology sets

 

 



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