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Lippincott Ch. 40

Immunosuppressants

QuestionAnswer
cyclosporin binds to cyclophilin forming a complex that binds to calcenurin
sirolimus binds to mTOR interfering with signal 3
tacrolimus binds to FKBP-12
azathioprine forms 6-MP then thioinosinic acid
mycophenolate mofetil forms MPA, which inhibits IMP
mycophenolate sodium created to minimize the GI effects associated with MMF
alemtuzumab directed CD52
antithymocyte globulins Ab against thymocytes
basiliximab binds to CD25
daclizumab binds to CD25 but more potent
muromonab-CD3 binds to CD3
methylprednisolone corticosteroid used for transplantation
prednisolone corticosteroid used for autoimmune conditions
prednisone corticosteroid used for transplantation or autoimmune conditions
Created by: cmueason
Popular Pharmacology sets

 

 



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