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IOS 9 Exam 2

OTIC

QuestionAnswer
Lubricant drops (OTC) Brand name *Lacri-tears *Genteal *Opti-tears *Tears
Lubricant drops (OTC) dose 1-2 drops into affected eye QD to prn
Lubricant drops (OTC) MOA Acts like mucin and stabilize tear film to reduce evaporation
Lubricant drops (OTC) common SE Crusting on eyelids, allergy to preservative
Lubricant ointments (OTC) ingredients White petrolatum, Mineral oil, Anhydrouslanolin, Hydroxypropylcellulose
Lubricant ointments (OTC) dosing Apply QD (often at bedtime) to prn
Lubricant ointments (OTC) MOA Acts like mucin and stabilize tear film to reduce evaporation
Lubricant ointments (OTC) SE Blurred vision
Mast cell stabilizer (Rx) Brands Opticrom, Crolom,Alomide,Alamast,Alocril
Mast cell stabilizer (Rx) Ingredients Cromolyn 4%,Lodoxamide 0.1%, Pemirolast 0.1%,Nedocromil 2%,
Opticrom, Crolom dosing 1 drop 4-6 times per day and then taper to BID as symptoms improve
Alomide dosing 1-2 drops QID for up to 3 months
Alamast dosing 1-2 drops BID-QID
Alocril dosing 1-2 drops BID
Mast cell stabilizer (Rx) MOA Decrease the degranulation of mast cells and prevent the release of inflammatory mediators
Mast cell stabilizer (Rx) SE HA, ocular burning/stinging, rhinitis
Antihistamine (Rx) Brand names Livostin, Emadine
Antihistamine (Rx) dosing 1 drop in each eye BID-QID
Antihistamine (Rx) MOA Relatively to highly selective H1 receptor antagonists
Antihistamine (Rx) SE Burning, stinging upon instillation; mydriasis, HA
Decongestant (OTC) Ingredients Naphazoline HCl, Tetrahydrozoline, Phenylephrine,Oxymetazoline HCl
Decongestant (OTC) dosing 1-2 drops in each eye QD-QID for all four agents
Decongestant (OTC) MOA Vasoconstriction to reduce redness, vascular congestion, eyelid edema
Decongestant (OTC) SE Conjunctivitis medicamentosa, stinging upon instillation, mydriasis
NSAIDS (Rx) Brand Acular
NSAIDS (Rx) dosing 1 drop in affected eye(s) QID up to 7 days
NSAIDS (Rx) MOA Inhibit COX, decreasing prostaglandins
NSAIDS (Rx) SE Hypersensitivity, transient burning/stinging (40%), dry eye, ocular infections, visual disturbancesCI: Pregnant women (3rd trimester)
Steroids (Rx) Brand Decadron, Maxidex, Pred Mild, FML,HMS, Lotemax, Alrex, Vexol
Steroids (Rx) Dosing 1 drop TID-QID Note: you may see 1 drop of the ophthalmic solution q hour while awake x 1 week and then reduced for severe cases
Steroids (Rx) MOA Decrease production of prostaglandins and leukotrienes
Steroids (Rx) SE Increased intraocular pressure (glaucoma), cataracts, predisposition to ocular infection, blurred vision, dry eye
Antihistamine and Mast Cell Stabilizer (Rx) Brand Patanol, Zaditor
Antihistamine and Mast Cell Stabilizer (Rx) Dosing 1-2 drops BID (space by 6-8 hours)
Antihistamine and Mast Cell Stabilizer (Rx) MOA H1 receptor antagonism and mast cell stabilization
Antihistamine and Mast Cell Stabilizer (Rx) SE Stinging upon administration and headache.
AntihistamineMast Cell Stabilizer, and Eosinophil inhibitor (Rx) Brand Optivar, Zaditor
AntihistamineMast Cell Stabilizer, and Eosinophil inhibitor (Rx) MOA H1 receptor antagonism, mast cell stabilization, and direct inhibitory effect on eosinophil chemotaxis and degranulation
AntihistamineMast Cell Stabilizer, and Eosinophil inhibitor (Rx) SE Conjunctival infection, HA, rhinitis, burning/stinging, bitter taste
Antihistamine and Decongestant (OTC) Brand Naphcon A, Opcon-A, Vasocon-A
Antihistamine and Decongestant (OTC) dosing 1-2 drops in each eye BID-QID
Antihistamine and Decongestant (OTC) MOA H1 receptor antagonism and Vasoconstriction to reduce redness, vascular congestion, eyelid edema
Antihistamine and Decongestant (OTC) SE Burning, stinging upon instillation; mydriasis, HA, conjunctivitis medicamentosa, stinging upon instillation
Antiviral (Rx) Brand Viroptic
Antiviral (Rx)- Viroptics generic name Trifluridine
Antiviral (Rx) Dosing 1 drop q2h while awake (9 drops max/day) until healed ulcer, then 1 drop q4h (5 drops max/day) x 7 more days not to exceed 21 days of therapy
Antiviral (Rx) MOA Inhibit DNA synthesis by inhibiting thymidylic phosphorylase which is needed for the incorporation of thymidine into the viral DNA
Antiviral (Rx) SE Burning, corneal edema, punctate lesions in corneal epithelium can occur with trifluridine cytotoxicity
Created by: liza001
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