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Autonomics-1.0

Pharmocology-Autonomics1.0/adrenergic receptor agonists

QuestionAnswer
What are Catecholamines? Direct acting agents
What drugs are catacholamines? NE, EPI, DA (direct or indirect), Dobutamine
NE works on what receptors? alpha, beta1
EPI works on what receptors? alpha, beta1, beta2
ISO works on what receptors? beta1, beta2
DA works on what receptors? beta1, renal D1, dose related
dobutamine works on what receptors? beta1selective, alpha1, beta2
What are noncatacholamines? direct acting agents
What drugs are noncatacholamines? Phenylephrine, methoxamine, Isoetherine, Metaproterenol, Terbutaline, Fenoterol, Albuterol, Pirbuterol
Phenylephrine and methoxamine works at what receptors? alpha
Isoetherine, Metaproterenol, Terbutaline, Fenoterol, Albuterol, and Pirbuterol works at what receptors? beta2, metaproterenol most potent
what are Indirect acting agonists? reserpine and cocaine
pretreat with cocaine, what is the response to direct agonist? indirect agonist? increased/decreased
pretreat reserpine, what is the response to direct agonist? indirect agonist? increased/decreased
agent for cardiac arrest/life support? EPI
cardiogenic or septic shock? continuous infusion of dobutamine, DA, EPI or NE
agent for CHF? dobutamine, DA (beta1)
agent for allergic reactions? EPI or other beta agonists
agent for local vascular effects? EPI, cocaine (prolong duration of anastetic)
agent priapism? alpha agonist local injection into penis
agent for nasal decongestant? alpha1 agonist
agent for athsma? beta agonist
agent to inhibit preterm labor? selective beta2 agonists
agent for HTN? central alpha2 agonist (clonidine)
pharmacologic use for EPI? bronchodialator, rapid allergic relief, prolong local anasthetic, restore cardiac rythm, vasopressor, hemostatic agent, glaucoma
pharmacologic use for NE? hypotension, increase PVR in shock
action and receptor for amphetamine dextroampetamine? indirect, alpha and beta
pharmacologic use for amphetamine dextroampetamine? obesity, narcolepsy, ADHD
action/receptor/pharmacologic use for cocaine? indirect, alpha and beta, topical hemostatic and local anasthetic
action/receptor/pharmacologic use for ephedrine? indirect and direct, alpha and beta, narcolepsy and obesity
pharmacologic use for ISO? emergancy heart block or bradycardia, pacemaker
pharmacologic use for dobutamine? acute HF, CHF, postop or postMI
pharmacologic use for DA? shock, hypotension, CHF, increase urine output (dopa vs beta receptor effect)
pharmacologic use for metoproternol? bronchodialator used in athsma
pharmacologic effects of terbutaline? bronchodialator and uterine relaxation
pharmacologic effects of ritodrine? uterine relaxation
pharmacologic effects of albuterol? bronchodialator used in athsma
pharmacologic effects of phenylephrine? mydriatic for retina exam, cardiothoracic surgury, nasal decongestant
pharmacologic effects of methoxamine? hypotension, PSVT (vagal effect)
pharmacologic effects of metaraminol? hypotension, PSVT (vagal effect)
pharmacologic effects of pseudoephedrine? nasal decongestant
pharmacologic effects of clonidine? antihypertensive agent, withdrawal symptoms, analgesic
pharmacologic effects of apraclonidine and brimonidine? opthalmic drops used in glaucoma
pharmacologic effects of guanfacine, guanabenz and methyldopa? antihypertensive agents
Created by: lmh9p4
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