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Histamine_PDA
Pharmacology, Medicinal
| Question | Answer |
|---|---|
| What type of receptors are histamines? | G-Protein Coupled Receptors |
| H-2 receptors are located where? What does it do? | Located on the vagus nerve, it promotes generation of stomach acid |
| H-3 Receptors found where? | CNS pre-synpatic neurons |
| H-3 receptors have same function as what type of receptors? | Alpha -2 |
| Inhibits the release of histamine when activated, what receptor does this? | H-3 |
| What are the administration routes of histamines? | P.O, Topically, Spray, Eye Drops |
| Which generation of histamines is given p.o and is metabolized by P450? | 2nd generation |
| Allegra, Claritin, Clarinex, Zyrtec, and Xyzal are which type of generation histamines? | 2nd generation |
| Effects of histamine include: | Vasodilation (H-1) vessels Edema Itching Constriction of Bronchioles (H-2) Secretion of H+ |
| H-2 blockers prevent H+ in the stomach which causes pH to increase or decrease? | Increase |
| H-2 blockers are used to treat what? | GERD Peptic Ulcer Z-E Syndrome |
| H2 antagonist are structurally related to? | Histamine |