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hypothalmic nuclei

brainstem and hypothalamic nuclei, projections and functions

QuestionAnswer
I. Olfactory nerve special somatic sensory innervates nasal epithelium and carries olfaction into frontal and temporal lobes
II. Optic nerve special somatic sensory comes from retina to LGN
III. Oculomotor nerve somatic motor and parasympathetic oculomotor--controls superior, inferior and medial recti, and inferior oblique Edinger-Westphal--pupil constrictor
IV. Trochlear nerve somatic motor innervates superior oblique
V. Trigeminal nerve somatosensation from the face and mouth motor fibers to muscles of mastication, crude touch, pain temperature, propriocepion and temperature from face spinal trigeminal, main sensory, mesencephalic, trigeminal motor
VI. Abducens somatic motor abducens nucleus lateral rectus
VII. Facial branchial motor, parasympathetic, special visceral sensory, general somatic sensory facial, superior salivatory, nucleus solitarious, spinal trigeminal
IX. Glossopharyngeal branchial motor, parasympathetic, general somatic sensory, special visceral sensory nucleus ambiguus, inferior salvitory, spinal trigeminal, nucleus solitarius
X. Vagus branchial motor, parasympathetic, special visceral sensory, general visceral sensory nucleus ambiguus, dorsal motor nucleus X, spinal trigeminal, nucleus solitarius
XI. Spinal accessory branchial motor spinal accessory nucleus sternocleidomastoid and trapezius
XII. Hypoglossal somatic motor hypoglossal nucleus intrinsic tongue muscles
Spinal trigeminal nucleus crude touch, pain, temperature and vibration of the face fibers from cranial nerves VII, IX, and X general somatic sensory
V1 opthalamic division top of head, forehead, eyes and bridge of nose
V2 maxillary division tip of nose and nasal cavity, temples, upper lip and cheeks
V3 mandibular division lower lip, jaw, tongue, and most of the ear
main sensory trigeminal nucleus convey fine touch, position sense, epicritic sensation general somatic sensory
mesencephalic nucleus of V general somatic sensory outside the PAG conveys proprioceptive information form the muscles of mastication and mediates the jaw jerk reflex
Motor nucleus of V branchial motor control the muscles of mastication descending corticobulbar tract synapses here
nucleus solitarius special and general visceral sensory nerves VII, IX, X receives taste information, carries taste information for epiglottis and pharynx, taste for posterior 1/3 of tongue
hypothalamus maintenance of homeostasis, regulation of drive-related behaviors and emotion, modulation of ANS, cortol of the pituitary gland receives blood-borne information and sends out hormones (blood-borne output)
dorsal longitudinal fasiculus located within the brainstem and travels through the PAG--descending tract from hyppothalamus to brainstem ascending tract carrying visceral information from the reticular formation to the hyppothalamus
anterior pituitary adenohypophysis controlled indirectly by hypothalamus releases TSH, dopamine and growth hormone Magnocellular neurons controls metabolism, milk production and growth hormones
posterior pituitary controlled directly from hypothalamus parvocellular neurons magnocellular (large) neuron axonsrun directly from hypothalamus into the posterior pituitay, the terminals release oxytocin and vasopressin directly into the circulation in the posterior pituitary
preoptic zone medial preoptic nucleus--releases gonadotropin releasing hormone which induces anterior pituitary to release LH and FSH Lateral preoptic nucleus--doesn't release hormones but has neurons with adenosine receptors important for sleep-wake cycles
Supraoptic area (anterior) paraventricular and supraoptic nuclei anterior, suprachiasmatic nuclei contains magnocellular neurons
magnocellular neurons secrete oxytocin and vassopressin in the posterior pituitary big neurons
parvocellular neurons produce and secrete releasing and inhibiting factors in the median eminence these substances influence hormone release in anterior pituitary small neurons
Anterior hypothalamic nucleus stimulation produces parasympathetic responses larger in heterosexual males
suprachiasmatic nucleus receives input from the retina to modulate circadian rhythms
Middle (tuberal) nuclei dorsomedial, ventromedial and arcuate nuclei
dorsomedial nucleus (hypothalamus) important for stimulating rage behaviors
ventromedial nucleus important for feeding behavior, and female sex behavior releases catecholamines which induce pancreas to secrete insulin
arcuate nucleus contains parvocellular neurons that release hormones to influence pituitary
Posterior nucleus stimulation provokes sympathetic responses (increased heart rate, breathing) and analgesia
mammilary bodies parcipates in limbic functions through connections with the hippocampus (fornix) Korsakoff's syndrome--degeneration of mammillary bodies
Fornix hippocampus through fornix to precommisural fibers to septal nuclei hippocampus through fornix to postcommisural fibers to mammillary bodies
stria terminalis from amygdala to many hypothalamic nuclei defensive reactions
dorsal longitudinal fasiculus orginates in midbrain tegmentum including PAG, locus coeruleus, and raphe nuclei and returning to the same places (through reticular formation) parasympathetic responses
Medial forebrain bundle axons from frontal cortex, stria terminalis, septal nuclei and olfactory regions of forebrain passing through lateral hypothalamus modulate visceral and somatic reactions in response to emotionally charged input
mammilothalamic tract mammillary bodies project to the anterior thalamus involved in memory and emotional expression
HPA stress reaction hypothalamus secretes CRH which stimulates the anterior pituitary to produce ACTH ACTH acts on adrenal cortex causing release of cortisol cortison bidns to glucocorticoid receptors
short term stress cortisol elevates blood sugar, suppresses immune system and lets Ca2+ into cels to increase responsitivity to input
prolonged psychological stress increased Ca2+ for prolonged periods leads to excitotoxicity which can damage hippocampus
median eminence devoid of a blood-brain barrier connects hypothalamus with anterior pituitary integral in hypophyseal portal system
anterior commissure connects two hemispheres specifically temporal lobes and amygdala
VIII. Vestibulocochlear special somatic sensory vestibular and cochlear innervates semicircular canals and cochlea
Created by: emward
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