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hypothalmic nuclei
brainstem and hypothalamic nuclei, projections and functions
Question | Answer | |
---|---|---|
I. Olfactory nerve | special somatic sensory | innervates nasal epithelium and carries olfaction into frontal and temporal lobes |
II. Optic nerve | special somatic sensory | comes from retina to LGN |
III. Oculomotor nerve | somatic motor and parasympathetic | oculomotor--controls superior, inferior and medial recti, and inferior oblique Edinger-Westphal--pupil constrictor |
IV. Trochlear nerve | somatic motor | innervates superior oblique |
V. Trigeminal nerve | somatosensation from the face and mouth motor fibers to muscles of mastication, crude touch, pain temperature, propriocepion and temperature from face | spinal trigeminal, main sensory, mesencephalic, trigeminal motor |
VI. Abducens | somatic motor abducens nucleus | lateral rectus |
VII. Facial | branchial motor, parasympathetic, special visceral sensory, general somatic sensory | facial, superior salivatory, nucleus solitarious, spinal trigeminal |
IX. Glossopharyngeal | branchial motor, parasympathetic, general somatic sensory, special visceral sensory | nucleus ambiguus, inferior salvitory, spinal trigeminal, nucleus solitarius |
X. Vagus | branchial motor, parasympathetic, special visceral sensory, general visceral sensory | nucleus ambiguus, dorsal motor nucleus X, spinal trigeminal, nucleus solitarius |
XI. Spinal accessory | branchial motor spinal accessory nucleus | sternocleidomastoid and trapezius |
XII. Hypoglossal | somatic motor hypoglossal nucleus | intrinsic tongue muscles |
Spinal trigeminal nucleus | crude touch, pain, temperature and vibration of the face | fibers from cranial nerves VII, IX, and X general somatic sensory |
V1 | opthalamic division | top of head, forehead, eyes and bridge of nose |
V2 | maxillary division | tip of nose and nasal cavity, temples, upper lip and cheeks |
V3 | mandibular division | lower lip, jaw, tongue, and most of the ear |
main sensory trigeminal nucleus | convey fine touch, position sense, epicritic sensation general somatic sensory | |
mesencephalic nucleus of V | general somatic sensory | outside the PAG conveys proprioceptive information form the muscles of mastication and mediates the jaw jerk reflex |
Motor nucleus of V | branchial motor | control the muscles of mastication descending corticobulbar tract synapses here |
nucleus solitarius | special and general visceral sensory nerves VII, IX, X | receives taste information, carries taste information for epiglottis and pharynx, taste for posterior 1/3 of tongue |
hypothalamus | maintenance of homeostasis, regulation of drive-related behaviors and emotion, modulation of ANS, cortol of the pituitary gland | receives blood-borne information and sends out hormones (blood-borne output) |
dorsal longitudinal fasiculus | located within the brainstem and travels through the PAG--descending tract from hyppothalamus to brainstem | ascending tract carrying visceral information from the reticular formation to the hyppothalamus |
anterior pituitary adenohypophysis | controlled indirectly by hypothalamus releases TSH, dopamine and growth hormone Magnocellular neurons | controls metabolism, milk production and growth hormones |
posterior pituitary | controlled directly from hypothalamus parvocellular neurons | magnocellular (large) neuron axonsrun directly from hypothalamus into the posterior pituitay, the terminals release oxytocin and vasopressin directly into the circulation in the posterior pituitary |
preoptic zone | medial preoptic nucleus--releases gonadotropin releasing hormone which induces anterior pituitary to release LH and FSH | Lateral preoptic nucleus--doesn't release hormones but has neurons with adenosine receptors important for sleep-wake cycles |
Supraoptic area (anterior) | paraventricular and supraoptic nuclei anterior, suprachiasmatic nuclei | contains magnocellular neurons |
magnocellular neurons | secrete oxytocin and vassopressin in the posterior pituitary | big neurons |
parvocellular neurons | produce and secrete releasing and inhibiting factors in the median eminence these substances influence hormone release in anterior pituitary | small neurons |
Anterior hypothalamic nucleus | stimulation produces parasympathetic responses | larger in heterosexual males |
suprachiasmatic nucleus | receives input from the retina to modulate circadian rhythms | |
Middle (tuberal) nuclei | dorsomedial, ventromedial and arcuate nuclei | |
dorsomedial nucleus (hypothalamus) | important for stimulating rage behaviors | |
ventromedial nucleus | important for feeding behavior, and female sex behavior | releases catecholamines which induce pancreas to secrete insulin |
arcuate nucleus | contains parvocellular neurons that release hormones to influence pituitary | |
Posterior nucleus | stimulation provokes sympathetic responses (increased heart rate, breathing) and analgesia | |
mammilary bodies | parcipates in limbic functions through connections with the hippocampus (fornix) | Korsakoff's syndrome--degeneration of mammillary bodies |
Fornix | hippocampus through fornix to precommisural fibers to septal nuclei | hippocampus through fornix to postcommisural fibers to mammillary bodies |
stria terminalis | from amygdala to many hypothalamic nuclei | defensive reactions |
dorsal longitudinal fasiculus | orginates in midbrain tegmentum including PAG, locus coeruleus, and raphe nuclei and returning to the same places (through reticular formation) | parasympathetic responses |
Medial forebrain bundle | axons from frontal cortex, stria terminalis, septal nuclei and olfactory regions of forebrain passing through lateral hypothalamus | modulate visceral and somatic reactions in response to emotionally charged input |
mammilothalamic tract | mammillary bodies project to the anterior thalamus | involved in memory and emotional expression |
HPA stress reaction | hypothalamus secretes CRH which stimulates the anterior pituitary to produce ACTH | ACTH acts on adrenal cortex causing release of cortisol cortison bidns to glucocorticoid receptors |
short term stress | cortisol elevates blood sugar, suppresses immune system and lets Ca2+ into cels to increase responsitivity to input | |
prolonged psychological stress | increased Ca2+ for prolonged periods leads to excitotoxicity which can damage hippocampus | |
median eminence | devoid of a blood-brain barrier connects hypothalamus with anterior pituitary | integral in hypophyseal portal system |
anterior commissure | connects two hemispheres specifically temporal lobes and amygdala | |
VIII. Vestibulocochlear | special somatic sensory vestibular and cochlear | innervates semicircular canals and cochlea |