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Ch. 28 BP

BP drugs

QuestionAnswer
Role of Renin-Angiotensin-Aldosterone System Renin produces Angiotensin 1 which is inactive until converted to Angiotensin 2 by ACE inhibitor. Angiotensin 2 stimulates the production of Aldosterone which increases the retention of H2O and Na which in turn increases the circulating volume. The increa
Lotensin ACE inhibitor
Cardura An alpha-1 blocker which causes vasodilation of retention and capacitance cells, thus, decreasing BP mainly diastolic. First-dose effect is orthostatic hypotension. Alpha-1 blockade causes increase in urine flow rate due to the relaxation of the smooth mu
Drugs for hypertensive crisis Nitroprussidde Nitropress, Diaxozide Hyperstat IV, Phentolamine Regitine
Effect of Diuretics in BP Promotes excretion of H2O and Na, decreasing circulatory volume, decreasing peripheral resistance, decreasing BP. Low-dose thiazide plus beta blocker and calcium channel blocker controls BP. Diuretics increase the efficacy of other antihypertensives.
Vasopressors Increases BP in hypovolemic shock to help support tissue perfusion.
Created by: cannislanda1
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