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Neuropharmacology

A Few Drugs and their Actions.

QuestionAnswer
Cycloserine weak partial agonist in NMDA system, has been effective in relieving negative symptoms in Schizophrenic patients.
Phencyclidine (PCP) binds to NMDA system
Ketamine Animal tranquilizer, binds to NMDA system
Down Regulation a drug blocks receptors which will say "slow down with production of NT
Up Regulation so much NT that the receptors increase
baclofen Agonist at GABA(B), Anticonvulsant, used for MS
Bicuculine Antagonist at the complex (GABA{A}), causes convulsions
Gabapentin decreases GABA release
Hydroxynipecotic Acid blocks transporter (GABA) and decreases reuptake
Diazepam (Benzodiazepine) Valium
Chlordiazepoxide (Benzodiazepine) Librium
Lorazepam (Benzodiazepine) Ativan
Alprazolam (Benzodiazepine) Xanax
Methoqualone (Ethanol)
Chloralhydrate (Ethanol) same # addicted to this in 1900 as there were alcoholics
Deprenyl and Tranylcypromine (Monoamines) originally developed as Blood Pressure medication but later turned out to treat Depression
Yohimbine NE-Alpha2-Adrenergic Antagonist
Fenflouramine (amphetamine) Breaks serotonin vesicles
Reserpine Antipsychotic, stops 5HT from entering vesicle
Fluoxetine (Prozac) blocks SERT whichs prevents serotonin reuptake
Buspirone (partial agonist to serotonin 1A) treats generalized anxiety
Sumatriptin (Partial agonist to serotonin 1D) very good migraine drug
Atropine and Scopalomine Muscarinic antagonists
Curare Nicotinic, stimulates and doesn't leave making it a blocker
Created by: EmptySpaces
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