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polipetidicos

antibioditocos polipeptidicos

QuestionAnswer
los bactericidas son aquellos que matan a las bacterias
son aquellos que impiden que se sigan reproduciendo las bacterias bacterioestaticos
LOs antibioticos polipeptidicos son sintetizados por microorganismos
Microorganismos taxonomicamente diferentes producen un mismo tipo de peptidos
Estructuralmente contienene agrupacion lipidicas y aminoacidos
Son ciclicos y resistentes a ____ vegetales y animales proteasas
Su estructura es compleja y ciclica
Familia de peptidos poco difusibles y con efectos toxicos polimixinas
Tirotricina, colistina, bacitacina son ejemplos de antibioticos ionoforos
Se designan con letras y numeros, clinicamente solo se usan las letras E y B
La colistina es la polimixina E
Son producidos por basilo polimyxa esporulado
Estos antibioticos se comportan como ___ ya que rompen membranas detergentes cationicos
Para su rea se utiliza la abreviatura de sus aminoacidos
Al romper membranas, destruyen el mec de transporte de bacterias por lo que hay un mayor escape de metabolitos e inhibidores de procesos celulares
Tienen un uso limitado debido a su toxicidad
Se usan en infecctiones urinarias y lesiones expuestas como... bacterecemia, meningitis, quemaduras, heridas infectadas, gastroenteritis
Son activas para bacterias gram positivas
No son activas frente a serratra, proteus , providencia
Sus reacciones adversas neurotoxicidad y nefrotoxicidad
Las bacterias pueden desarrollar resistencia
Con bacitracina se puede producir sensibilizacion cruzada
La polimixina E se llama Colistina
La colistina se administra en forma de sulfatos
Puede tener uso externo colistina
Bacitracina provoca nefrotoxicidad
La bacitricina es util para bacterias gram postivias, y se usa en caso de clostridium y treponema pallidium
En gram negativa: reiseenia gonorrea y meniningitidis
Se usa como complementeo dietaria en ganaderia Bacitracina
La bacitricina no rompe membrana, sino que inhibe sintesis de pared bacteriana y desfosforilacion
Interrumpir tratamiento si hay disminucion de diuresis
Created by: elei2
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