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Chapter 19

TermDefinition
Osteoarthritis Worn cartilage so bone rubs bone. Knees, hips, spine, hands, and feet. No cure; treatment slows it and treats pain.
Osteoporosis Low bone mass and brittle bone. The danger is fracture. Common after menopause.
Gout Arthritis from uric acid crystals in a joint, often the big toe. Sudden and severe.
COX-1 Enzyme that protects the stomach lining and helps platelets stick. Blocking it can cause ulcers and bleeding.
COX-2 Enzyme at the site of injury. Blocking it reduces swelling and pain.
Analgesic A drug that relieves pain.
Antipyretic A drug that reduces fever.
Reye syndrome Rare brain and liver injury linked to aspirin in children or teens during a viral illness.
Acetaminophen (Tylenol) Pain and fever. Does not treat swelling or thin blood. Misuse is the most common cause of liver failure, often from combo products.
Aspirin Pain, fever, and swelling. Also thins blood. Do not give to children because of Reye syndrome.
Ibuprofen (Advil, Motrin) NSAID. Pain and swelling. Take with food. Watch stomach, kidneys, and bleeding.
Naproxen (Aleve, Naprosyn) & Meloxicam (Mobic) NSAID. Pain and swelling. Take with food.
Celecoxib (Celebrex) COX-2 selective NSAID. Aims to spare the stomach. Still has heart risk.
Alendronate (Fosamax) Weekly osteoporosis tablet. Full glass of water. Stay upright so it does not burn the esophagus.
Allopurinol (Zyloprim) Gout prevention. Lowers uric acid. Not the drug for the acute attack.
Colchicine Drug for an acute gout attack, along with an NSAID or a steroid burst
Cyclobenzaprine (Flexeril) Skeletal muscle relaxant for spasm. Causes drowsiness. Avoid alcohol.
Methocarbamol (Robaxin) & Tizanidine (Zanaflex) Skeletal muscle relaxant. Causes drowsiness. Avoid alcohol.
Carisoprodol (Soma) Muscle relaxant. Schedule IV. Short-term only. Extra handling.
Hydrocodone/acetaminophen (Norco) Opioid combo. Schedule II. No phone refills. Acetaminophen ceiling still applies.
Tramadol (Ultram) Opioid-like pain drug. Schedule IV. Still controlled.
Succinylcholine Depolarizing neuromuscular blocker used in surgery. Not a retail fill. Paralyzes skeletal muscle, including breathing muscle.
Methyl salicylate (Bengay, IcyHot) Topical pain ingredient with menthol. Hot or cold distraction. Less stomach exposure than an oral NSAID.
Created by: tomknoah
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