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Gout
MSK Gout pharmacology
| questions | answers |
|---|---|
| What is Gout? | arthritis subtype associated with hyperuricemia |
| Crystal deposits that cause | inflammation, tactile pain and bone erosion |
| affected areas are | feet (toes), hands (fingers), kidney (chronic) |
| risk factors | Age, male/menopausal women, obesity/dianetes/insulin resistance, asymptomatic hyperuricemia |
| High uric acid | increase insulin resistance |
| insulin resistance | increase circulation of uric acid |
| low temperature, low pH | Increases uric acid |
| which drug decreases uric acid production | Allopurinol/ febuxostat |