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Cardio 1
BDK knowledge Cardio 1
| Pharmacologic Catergory | Generic Name | Brand name | Common indications | Essential Knowledge |
|---|---|---|---|---|
| ACE inhibitor | benazepril (PO) | Lotensin | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ACE inhibitor | enalapril (PO) | Vasotec | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ACE inhibitor | lisinopril (PO) | Prinivil, Zestril | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ACE inhibitor | ramipril (PO) | Altace | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ARB | irbesartan(PO) | Avapro | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ARB | losartan (PO) | Cozaar | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ARB | olmesartan (PO) | Benicar | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ARB | valsartan (PO) | Diovan | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ARB & neprilysin inhibitor (ARNI) | Valsartan & sacubitril (PO) | Entresto | HF | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) Other Notes: Do not use within 36 hours of an ACE inhibitor |
| Dihydropyridine Calcium channel blocker (CCB) | amlodipine (PO) | Norvasc | HTN, HF, CAD | Key Side Effects: peripheral edema, hypotension |
| Dihydropyridine Calcium channel blocker (CCB) | nifedipine (PO) | Procardia XL, Adalat CC | HTN, HF, CAD | Key Side Effects: peripheral edema, hypotension |
| Dihydropyridine Calcium channel blocker (CCB) | nicardipine (PO) | Cardene | Hypertensive crisis | Key Side Effects: flushing, headache, peripheral edema, hypotension |
| Non-dihydropyridine CCB | diltiazem (PO,IV) | Carter XT, Cardizem CD, Cardizem LA, Cardizem, Tiazac | AF (rate control), HTN, CAD | Key Side Effects: bradycardia, constipation, peripheral edema, hypotension |
| Non-dihydropyridine CCB | verapamil (PO) | Calan SR, Verelan | AF (rate control), HTN, CAD | Key Side Effects: bradycardia, constipation, peripheral edema, hypotension |
| Thiazide diuretic | hydrochlorothiazide (PO) | ------- | HTN | Key Side Effects: hypokalemia, hyponatremia, photosensitivity, hypotension |
| Thiazide- related diuretic | chlorthalidone (PO) | Thalitone | HTN | Key Side Effects: hypokalemia, hyponatremia, photosensitivity, hypotension |
| Dihydropyridine Calcium channel blocker (CCB) & ACE | amlodipine and benazepril (PO) | Lotrel | HTN, HF, CAD | Key Side Effects: peripheral edema, hypotension,cough, hyperkalemia, angioedema. US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ACE & Thiazide diuretic | lisinopril and hydrochlorothiazide (PO) | Zestoretic | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension, , hyponatremia, photosensitivity,hypokalemia, US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ARB & Thiazide diuretic | losartan and hydrochlorothiazide (PO) | Hyzaar | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension, hypokalemia, hyponatremia, photosensitivity, US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ARB & Thiazide diuretic | olmesartan and hydrochlorothiazide (PO) | Benicar-HCT | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension, hypokalemia, hyponatremia, photosensitivity, US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| ARB & Thiazide diuretic | valsartan and hydrochlorothiazide (PO) | Diovan-HCT | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension,hypokalemia, hyponatremia, photosensitivity, US Boxed Warnings: fetal toxicity (CI in pregnancy) |