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CNS - 3
| Generic | Brand | Catagory | Class | Indications | Essential Knowledge |
|---|---|---|---|---|---|
| lithium (PO) | Lithobid | Antimanic agent | N/a | Bipolar disorder | Side Effects: tremor, acne, hypothyroidism, weight gain, polyuria, polydipsia, GI upset Boxed Warnings: ability to promptly monitor levels is necessary Other: narrow therapeutic index drug; avoid in pregnancy |
| sumatriptan (PO, intranasal, SQ) | Imitrex | Antimigraine | N/a | Migraine | Side Effects: fatigue, somnolence, dizziness, chest tightness, paresthesia Other: CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension |
| rizatriptan (PO) | Maxalt | Antimigraine | N/a | Migraine | Side Effects: fatigue, somnolence, dizziness, chest tightness, paresthesia Other: CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension |
| haloperidol (PO, IV, IM) | Haldol | First-generation antipsychotic | N/a | Schizophrenia | Side Effects: sedation, EPS, parkinsonism, xerostomia, orthostatic hypotension, weight gain, QTc prolongation Boxed Warnings: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death |
| clozapine (PO) | Clozaril | Second-generation antipsychotic | N/a | Treatment-resistant schizophrenia | SE: sedation, constipation, orthostatic hypotension, sialorrhea, hyperglycemia, weight gain, neutropenia BW: may cause severe neutropenia; orthostatic hypotension, bradycardia, and syncope; seizures; fatal myocarditis and cardiomyopathy; elderly patie |
| aripiprazole (PO, IM) | Abilify (PO/IM), Aristada (IM) | Second-generation antipsychotic | N/a | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | S.E.: akathisia, restlessness, sedation, EPS, constipation, orthostatic hypotension, weight gain Boxed Warnings: antidepressants increase the risk of suicidal thinking; elderly patients with dementia at increased risk of death |
| quetiapine (PO) | Seroquel, Seroquel XR | Second-generation antipsychotic | N/a | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Side Effects: sedation, EPS, constipation, orthostatic hypotension, weight gain US Boxed Warnings: antidepressants increase the risk of suicidal thinking; elderly patients with dementia at increased risk of death |
| lurasidone (PO) | Latuda | Second-generation antipsychotic | N/a | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Side Effects: sedation, EPS, constipation, orthostatic hypotension, lbs gain Boxed Warnings: antidepressants increase the risk of suicidal; elderly patients with dementia at increased risk of death Other: CI with strong 3A4 inhibitors and inducers |
| olanzapine (PO, IM) | Zyprexa | Second-generation antipsychotic | N/a | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Side Effects: sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia Boxed Warnings: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death |
| risperidone (PO, IM) | Risperdal (PO), Risperdal Consta (IM) | Second-generation antipsychotic | N/a | Schizophrenia | Side Effects: sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia Boxed Warnings: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death |