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Infectious Disease 3
BDK
| Category | Generic | Brand | Class | Indication | Essential knowledge | |
|---|---|---|---|---|---|---|
| Lincosamide antibiotic | clindamycin (PO, IV) | Cleocin | Pharyngitis, SSTI, syphilis (IV/IM) Activity against: Streptococcus pyogenes, Treponema pallidum (syphilis) | Key Side Effects: diarrhea, Clostridioides difficile diarrhea US Boxed Warnings: Clostridioides difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin, and may range in severity from m | ||
| Sulfonamide antibiotic | sulfamethoxazole and trimethoprim (PO, IV) | Bactrim, Bactrim DS | Otitis media, pharyngitis Activity against: Streptococcus pneumoniae, Streptococcus pyogenes | Key Side Effects: nausea, vomiting, diarrhea, skin rashes (rarely SJS or TEN), photosensitivity, crystalluria, hyperkalemia, increased serum creatinine, hypersensitivity reactions | ||
| Urinary antibiotic | nitrofurantoin (PO) | Macrobid | Otitis media, bacterial sinusitis Activity against: MSSA, Streptococcus pneumoniae, anaerobes, Enterobacteriacae | Key Side Effects: nausea, pulmonary fibrosis (chronic use | ||
| Aminoglycoside antibiotic | tobramycin (IV, inhaled) | Tobi (inhaled) | Key Side Effects: nephrotoxicity, ototoxicity | |||
| Glycopeptide antibiotic | vancomycin (IV, PO) | Vancocin | Key Side Effects: nephrotoxicity, vancomycin infusion reaction, ototoxicity | |||
| Antibiotic | metronidazole (PO, IV) | Flagyl | Key Side Effects: nausea, metallic taste, disulfiram reaction with alcohol, peripheral neuropathy (long-term use) | |||
| Antibiotic | mupirocin (topical) | Bactroban | Key Side Effects: no major side effects | |||
| Topical antibiotic | neomycin + polymyxin B + bacitracin (topical, ophthalmic) | Topical: Neosporin Ophthalmic: Neo-Polycin | Neosporin: OTC | Key Side Effects: reddening, itching | ||
| Urinary antibiotic | fosfomycin (PO) | Monurol | Key Side Effects: headache, diarrhea, nausea | |||