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Infections
infection cycle, transmission, types
| Term | Definition |
|---|---|
| pathogenesis | the actual act of causing a disease |
| pathogen | an organism that can cause disease |
| professional pathogen | an organism that is not considered normal flora but can cause disease |
| opportunistic pathogen | an organism that is considered normal flora and can cause disease |
| virulence factor | a type of gene within pathogens that affects its ability to cause disease |
| infectious stages | entry, adhesion, invasion, disease, exit |
| exogenous agent | a pathogen that came from outside the body |
| endogenous agent | a pathogen that was originally on or in the body |
| portals of entry | skin, GI, respiratory, urogenital, transplacental, perinatal |
| STORCH complex | the handful of pathogens that a fresh baby is capable of being infected with |
| STORCH compex | syphilis, taxoplasmosis, other diseases, rubella, cytomegalovirus, and herpes simplex virus |
| adhesion | a pathogen grabbing onto the host |
| host range | the type of host a pathogen can colonize |
| tissue tropism | the type of tissue a pathogen can colonize |
| host's defenses | cells that destroy microbes and chemicals that destroy microbes |
| periods of an acute infection | incubation, prodromal, period of invasion, convalescent |
| incubation | before growth and damge, microbe is being estabished |
| prodromal | damage is starting to happen, host is having nonspecific feelings of being unwell but cannot identify cause |
| period of invasion | symptoms are severe and specific to disease, significant amount of damage |
| convalescent period | disease is being defeated by immune system |
| acute infection | a short and self-limiting infection |
| chronic infection | progress and persist over a long period of time |
| asymptomatic phase | pathogen is multiplying in the host but damage is insufficient |
| latent phase | host is infected but is starting to recover due to the microbe becoming dormant |
| sequelae | long-lasting damage caused by a disease that has since resolved |
| localized infection | microbial infection confined to a specific area and tissue |
| septicemia | presence of microbes in blood |
| bacteremia | large amount of bacteria in the blood |
| mixed infection | several types of microbes growing in the same infection site |
| reservoir | primary place a pathogen will be |
| examples of reservoir | animals, food, water, plants, soil |
| passive carrier | carrier but is not infected |
| asympomatic carrier | shows no symptoms but is infected |
| incubation carrier | spreads the infection during its incubation period |
| convalescent carrier | recuperating without symptoms but still spreading disease |
| zoonotic disease | a disease that is indigenous to animals but can be transmitted to humans |
| infectious disease | microorganism grows and reproduces in or on the host organism |
| communicable disease | disease that can be transmitted from host to host |
| contagious disease | a disease that is easily spread from host to host |
| non-contagious infectious disease | a disease that is not spread from host to host but the host's own flora or the host coming in contact with organism in its reservoir |
| direct transmission | immediate contact with the infected host or their fluids |
| indirect transmission | not directly contacting the host or their fluids |
| vector | a carrier that's not a human |
| vehicle | an inanimate object that a microbe can use to transfer |
| fomite | an inanimate object that a human touches |
| morality rate | total number of deaths in a population |
| morbidity rate | total number of people infected |
| case fatality rate | percentage of known cases that result in death |
| prevalence | how common the disease is |
| incidence | the number of cases within a period of time |
| outbreak | an unexpected increase in a disease's incidence |
| endemic | steady incidence of a disease in a specific geographic location |
| sporadic | occasional cases at irregular intervals |
| epidemic | large disease outbreak |
| pandemic | epidemic across continents |
| nosocomial infection | hospital-acquired infection |