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Q1 - Pharmacotherapy

Quarter 1 Pharmacotherapy

Generic nameDrug overview
lisinopril Brand name: Zestril; Prinivil Class: ACE Inhibitor Indication: Hypertension Pearls: - ACE inhibitors may cause a dry cough - ACE inhibitors are contraindicated in pregnancy
benazepril Brand name: Lotensin Class: ACE Inhibitor Indication: Hypertension Pearls: - ACE inhibitors may cause a dry cough - ACE inhibitors are contraindicated in pregnancy
ramipril Brand name: Altace Class: ACE Inhibitor Indication: Hypertension Pearls: - ACE inhibitors may cause a dry cough - ACE inhibitors are contraindicated in pregnancy
enalapril Brand name: Vasotec Class: ACE Inhibitor Indication: Hypertension Pearls: - ACE inhibitors may cause a dry cough - ACE inhibitors are contraindicated in pregnancy
losartan Brand name: Cozaar Class: ARB Indication: Hypertension Pearls: - Like ACE-I's, ARBs are also contraindicated in pregnancy - Unlike ACE-I's, ARBs do NOT cause cough
olmesartan Brand name: Benicar Class: ARB Indication: Hypertension Pearls: - Like ACE-I's, ARBs are also contraindicated in pregnancy - Unlike ACE-I's, ARBs do NOT cause cough
irbesartan Brand name: Avapro Class: ARB Indication: Hypertension Pearls: - Like ACE-I's, ARBs are also contraindicated in pregnancy - Unlike ACE-I's, ARBs do NOT cause cough
valsartan Brand name: Diovan Class: ARB Indication: Hypertension Pearls: - Like ACE-I's, ARBs are also contraindicated in pregnancy - Unlike ACE-I's, ARBs do NOT cause cough
metoprolol tartrate Brand name: Lopressor Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Metoprolol tartrate is taken twice daily (as opposed to once daily for succinate) - Beta-blockers should be avoided in patients with asthma
metoprolol succinate Brand name: Toprol XL Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Metoprolol succinate is taken once daily (as opposed to twice daily for tartrate) - Beta-blockers should be avoided in patients with asthma
carvedilol Brand name: Coreg Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Beta-blockers should be avoided in patients with asthma - Take with food
atenolol Brand name: Tenormin Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Beta-blockers should be avoided in patients with asthma
labetalol Brand name: Trandate Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Beta-blockers should be avoided in patients with asthma
propranolol Brand name: Inderal Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Beta-blockers should be avoided in patients with asthma
amlodipine Brand name: Norvasc Class: Calcium channel blocker (dihydropyridine) Indication: Hypertension Pearls:
nifedipine Brand name: Procardia; Adalat Class: Calcium channel blocker (dihydropyridine) Indication: Hypertension Pearls:
diltiazem Brand name: Cardizem Class: Calcium channel blocker (non-dihydropyridine) Indication: Hypertension Pearls:
verapamil Brand name: Calan Class: Calcium channel blocker (non-dihydropyridine) Indication: Hypertension; atrial fibrillation Pearls:
hydrochlorothiazide Brand name: Microzide Class: Thiazide diuretic Indication: Hypertension Pearls: - Common abbreviation: HCTZ - Diuretics are typically taken in the morning
chlorthalidone Brand name: Thalitone Class: Thiazide diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning
metolazone Brand name: Zaroxolyn Class: Thiazide diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning
losartan / hydrochlorothiazide Brand name: Hyzaar Class: Combination of ARB + Thiazide diuretic Indication: Hypertension Pearls: - Take in the morning (diuretic) - Avoid in pregnancy (ARB)
lisinopril / hydrochlorothiazide Brand name: Zestoretic Class: Combination of ACE-I + Thiazide diuretic Indication: Hypertension Pearls: - Take in the morning (diuretic) - Avoid in pregnancy (ACE-I)
furosemide Brand name: Lasix Class: Loop diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - Can cause hypokalemia (low potassium). Many patients take a potassium supplement.
bumetanide Brand name: Bumex Class: Loop diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - Can cause hypokalemia (low potassium). Many patients take a potassium supplement.
torsemide Brand name: Demadex Class: Loop diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - Can cause hypokalemia (low potassium). Many patients take a potassium supplement.
spironolactone Brand name: Aldactone Class: Potassium-sparing diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - Can cause hyperkalemia (high potassium) - Avoid high-potassium foods and salt substitutes like Dash
triamterene / hydrochlorothiazide Brand name: Dyazide Class: Potassium-sparing diuretic + thiazide diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - ADR: hyperkalemia (high potassium) - Avoid high-potassium foods / salt substitutes like Dash
potassium chloride Brand name: Klor-Con; K-Dur; K-Tab Class: Potassium supplement Indication: Prevent/treat hypokalemia Pearls: - Abbreviation: KCl - Replaces potassium lost from loop/thiazides - Available as: tabs, caps, powder, solution - Solution must be diluted
doxazosin Brand name: Cardura Class: Alpha 1 blocker Indication: Hypertension; BPH Pearls: - ADR: Orthostatic hypotension. Patients should rise slowly from sitting or lying positions - Alpha 1 blockers can treat HTN, BPH, or both. Doxazosin treats both.
terazosin Brand name: Hytrin Class: Alpha 1 blocker Indication: Hypertension; BPH Pearls: - ADR: Orthostatic hypotension. Patients should rise slowly from sitting or lying positions - Alpha 1 blockers can treat HTN, BPH, or both. Terazosin treats both.
prazosin Brand name: Minipress Class: Alpha 1 blocker Indication: Hypertension Pearls: - ADR: Orthostatic hypotension. Patients should rise slowly from sitting/lying positions - Alpha 1 blockers can treat HTN, BPH, or both. Prazosin treats HTN only.
tamsulosin Brand name: Flomax Class: Alpha 1 blocker Indication: BPH Pearls: - ADR: Orthostatic hypotension. Patients should rise slowly from sitting or lying positions - Alpha 1 blockers can treat HTN, BPH, or both. Tamsulosin treats BPH only.
hydralazine Brand name: Apresoline Class: Peripheral vasodilator Indication: Hypertension Pearls: - ADR: orthostatic hypotension. Patients should rise slowly from sitting or lying positions
clonidine Brand name: Catapress; Kapvay Class: Alpha 2 adrenergic agonist Indication: Hypertension; ADHD Pearls: - ADR: orthostatic hypotension. Patients should rise slowly from sitting or lying positions
aspirin Brand name: Various Class: NSAID; Salicylate Indication: Antiplatelet (low dose); Analgesic/antipyretic (high dose) Pearls: - Low-dose "baby aspirin" should never be given to infants - ADR: Increased bleeding risk - Abbreviation: ASA
clopidogrel Brand name: Plavix Class: Antiplatelet Indication: Prevent blood clots Pearls: - ADR: Increased risk of bleeding
ticagrelor Brand name: Brilinta Class: Antiplatelet Indication: Prevent blood clots Pearls: - ADR: Increased risk of bleeding
warfarin Brand: Coumadin Class: Anticoagulant Indication: Prevent/treat clots Pearls: - Boxed warning: Risk of bleeding - Maintain consistent vitamin K intake - Antidote: Vitamin K (phytonadione) - Hazardous drug - Frequent blood monitoring / dose changes
apixaban Brand name: Eliquis Class: Anticoagulant Indication: Prevent/treat blood clots Pearls: - ADR: Increased risk of bleeding
dabigatran Brand name: Pradaxa Class: Anticoagulant Indication: Prevent/treat blood clots Pearls: - ADR: Increased risk of bleeding
enoxaparin Brand name: Lovenox Class: Anticoagulant Indication: Prevent/treat blood clots Pearls: - ADR: Increased risk of bleeding - Administered via injection
rivaroxaban Brand name: Xarelto Class: Anticoagulant Indication: Prevent/treat blood clots Pearls: - ADR: Increased risk of bleeding
nitroglycerin sublingual Brand name: Nitro-Quick; Nitro-Stat Class: Vasodilator Indication: Angina Pearls: - SL tablet or spray. - Use 1 dose q 5 min PRN for up to 3 doses. Call 911 if no relief - DDI: PDE5-inhibitors (sildenafil, tadalafil) - Store in original container
isosorbide / hydralazine Brand name: BiDil Class: Vasodilator Indication: Prevents angina (heart pain) Pearls: - DDI: PDE5-inhibitors (sildenafil, tadalafil etc.) Administering together may lead to heart attack or stroke.
digoxin Brand name: Lanoxin; Digitek Class: Cardiac glycoside Indication: Heart failure; arrhythmia Pearls: - Narrow therapeutic index drug
atorvastatin Brand name: Lipitor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis.
rosuvastatin Brand name: Crestor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis.
simvastatin Brand name: Zocor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis.
pravastatin Brand name: Pravachol Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis.
lovastatin Brand name: Mevacor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis.
ezetimibe Brand name: Zetia Class: Antilipemic agent Indication: Hypercholesterolemia (high cholesterol) Pearls: - Decreases cholesterol absorption in the intestine - Often used with a statin
fenofibrate Brand name: Tricor; Trilipix Class: Fibrate Indication: Hypercholesterolemia (high cholesterol) Pearls: - Increased risk of muscle toxicity when combined with statins
gemfibrozil Brand name: Lopid Class: Fibrate Indication: Hypercholesterolemia (high cholesterol) Pearls: - Increased risk of muscle toxicity when combined with statins
Niacin Brand name: Niaspan Class: Antilipemic agent Indication: Hypercholesterolemia Pearls: - Also known as vitamin B3 or nicotinic acid - ADR: Flushing - temporary and harmless. Taking aspirin can help reduce it. - Also available in OTC formulations
omega-3 fatty acids Brand name: Lovaza Class: Antilipemic agent Indication: Hypercholesterolemia (high cholesterol) Pearls: - Available in OTC and Rx formulations
albuterol inhaler Brand name: ProAir; Ventolin; Proventil Class: SABA (Short-acting beta agonist) Indication: Bronchospasm Pearls: - Albuterol MDIs (metered-dose inhalers) are commonly referred to as "rescue inhalers" - ADR: Increased heart rate; palpitations
levalbuterol inhaler Brand name: Xopenex Class: SABA (Short-acting beta agonist) Indication: Bronchospasm Pearls: - Levalbuterol MDIs (metered-dose inhalers) are commonly referred to as "rescue inhalers" - ADR: Increased heart rate; palpitations
albuterol nebulizer solution Brand name: N/A Class: SABA (Short-acting beta agonist) Indication: Bronchospasm Pearls: - Must be administered using a nebulizer - ADR: Increased heart rate; palpitations
fluticasone inhaler Brand name: Flovent Class: ICS (Inhaled corticosteroid) Indication: Asthma maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush)
beclomethasone Brand name: Qvar Class: ICS (Inhaled corticosteroid) Indication: Asthma maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush)
tiotropium Brand name: Spiriva Class: LAMA (Long-acting muscarinic agent) Indication: Asthma/COPD maintenance Pearls:
umeclidinium Brand name: Incruse Class: LAMA (Long-acting muscarinic agent) Indication: Asthma/COPD maintenance Pearls:
salmeterol Brand name: Serevent Class: LABA (Long-acting beta agonist) Indication: Asthma/COPD maintenance Pearls:
formoterol / budesonide Brand name: Symbicort Class: LABA / ICS Indication: Asthma/COPD maintenance and/or rescue Pearls: - Can be used for SMART therapy (single maintenance and reliever inhaler) - Rinse mouth after ICS use (prevents oral thrush)
salmeterol / fluticasone Brand name: Advair Class: LABA / ICS Indication: Asthma/COPD maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush)
vilanterol / fluticasone Brand name: Breo Ellipta Class: LABA / ICS Indication: Asthma/COPD maintenance Pearls:
formoterol / mometasone Brand name: Dulera Class: LABA / ICS Indication: Asthma/COPD maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush)
vilanterol / umeclidinium Brand name: Anoro Ellipta Class: LABA / LAMA Indication: Asthma/COPD maintenance Pearls:
vilanterol / umeclidinium / fluticasone Brand name: Trelegy Ellipta Class: LABA / LAMA / ICS Indication: Asthma/COPD maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush)
montelukast Brand name: Singulair Class: Leukotriene-receptor antagonist Indication: Asthma maintenance; allergy management Pearls: - Boxed warning: Neuropsychiatric events (e.g., depression, suicidal thoughts). More common during initiation and dosage changes.
nicotine patches Brand name: Nicoderm Class: NRT (nicotine replacement therapy) Indication: Smoking cessation Pearls: - Available OTC - Apply to clean, dry skin; rotate sites daily
nicotine gum Brand name: Nicorette Gum Class: NRT (nicotine replacement therapy) Indication: Smoking cessation Pearls: - Available OTC - Patients should use the "chew-and-park" method
nicotine lozenge Brand name: Nicorette Lozenge Class: NRT (nicotine replacement therapy) Indication: Smoking cessation Pearls: - Available OTC - Allow to dissolve in mouth. Do not chew or swallow whole.
varenicline Brand name: Chantix Class: Nicotinic receptor agonist Indication: Smoking cessation Pearls: - Prescription only
bupropion SR Brand name: Zyban; Wellbutrin Class: Norepinephrine/dopamine reuptake inhibitor Indication: Antidepressant; smoking cessation; ADHD Pearls: - IR and ER (Wellbutrin, Wellbutrin XL) used for depression/ADHD - SR (Zyban) used for smoking cessation
levothyroxine Brand name: Synthroid; Levoxyl Class: Thyroid hormone replacement Indication: Hypothyroidism (low levels of thyroid hormone) Pearls: - Narrow therapeutic index drug (NTI) - Take on an empty stomach, same time daily
epinephrine injector Brand name: EpiPen Class: Sympathomimetic Indication: Anaphylaxis Pearls: - Emergency rescue injection for severe allergic reactions
testosterone injection Brand name: Depo-testosterone Class: Androgen Indication: Male hypogonadism Pearls: - Injectable testosterone replacement - DEA Schedule III
testosterone gel Brand name: Androgel Class: Androgen Indication: Male hypogonadism Pearls: - Topical testosterone replacement - DEA Schedule III - Risk of accidental transfer. Avoid direct skin contact with women/children. Apply to covered areas
conjugated estrogens Brand name: Premarin Class: Estrogen Indication: Menopausal symptom relief Pearls: - Hormone replacement therapy (HRT)
oral contraceptives Brand name: Various Class: Hormones Indication: Birth control Pearls: May contain a combination of many hormones, including: estradiol, levonorgestrel, norgestimate, norethindrone, drospirenone, and progesterone.
Created by: pta78
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