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Q1 - Pharmacotherapy
Quarter 1 Pharmacotherapy
| Generic name | Drug overview |
|---|---|
| lisinopril | Brand name: Zestril; Prinivil Class: ACE Inhibitor Indication: Hypertension Pearls: - ACE inhibitors may cause a dry cough - ACE inhibitors are contraindicated in pregnancy |
| benazepril | Brand name: Lotensin Class: ACE Inhibitor Indication: Hypertension Pearls: - ACE inhibitors may cause a dry cough - ACE inhibitors are contraindicated in pregnancy |
| ramipril | Brand name: Altace Class: ACE Inhibitor Indication: Hypertension Pearls: - ACE inhibitors may cause a dry cough - ACE inhibitors are contraindicated in pregnancy |
| enalapril | Brand name: Vasotec Class: ACE Inhibitor Indication: Hypertension Pearls: - ACE inhibitors may cause a dry cough - ACE inhibitors are contraindicated in pregnancy |
| losartan | Brand name: Cozaar Class: ARB Indication: Hypertension Pearls: - Like ACE-I's, ARBs are also contraindicated in pregnancy - Unlike ACE-I's, ARBs do NOT cause cough |
| olmesartan | Brand name: Benicar Class: ARB Indication: Hypertension Pearls: - Like ACE-I's, ARBs are also contraindicated in pregnancy - Unlike ACE-I's, ARBs do NOT cause cough |
| irbesartan | Brand name: Avapro Class: ARB Indication: Hypertension Pearls: - Like ACE-I's, ARBs are also contraindicated in pregnancy - Unlike ACE-I's, ARBs do NOT cause cough |
| valsartan | Brand name: Diovan Class: ARB Indication: Hypertension Pearls: - Like ACE-I's, ARBs are also contraindicated in pregnancy - Unlike ACE-I's, ARBs do NOT cause cough |
| metoprolol tartrate | Brand name: Lopressor Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Metoprolol tartrate is taken twice daily (as opposed to once daily for succinate) - Beta-blockers should be avoided in patients with asthma |
| metoprolol succinate | Brand name: Toprol XL Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Metoprolol succinate is taken once daily (as opposed to twice daily for tartrate) - Beta-blockers should be avoided in patients with asthma |
| carvedilol | Brand name: Coreg Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Beta-blockers should be avoided in patients with asthma - Take with food |
| atenolol | Brand name: Tenormin Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Beta-blockers should be avoided in patients with asthma |
| labetalol | Brand name: Trandate Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Beta-blockers should be avoided in patients with asthma |
| propranolol | Brand name: Inderal Class: Beta-blocker Indication: Hypertension; heart failure, arrhythmia Pearls: - Beta-blockers should be avoided in patients with asthma |
| amlodipine | Brand name: Norvasc Class: Calcium channel blocker (dihydropyridine) Indication: Hypertension Pearls: |
| nifedipine | Brand name: Procardia; Adalat Class: Calcium channel blocker (dihydropyridine) Indication: Hypertension Pearls: |
| diltiazem | Brand name: Cardizem Class: Calcium channel blocker (non-dihydropyridine) Indication: Hypertension Pearls: |
| verapamil | Brand name: Calan Class: Calcium channel blocker (non-dihydropyridine) Indication: Hypertension; atrial fibrillation Pearls: |
| hydrochlorothiazide | Brand name: Microzide Class: Thiazide diuretic Indication: Hypertension Pearls: - Common abbreviation: HCTZ - Diuretics are typically taken in the morning |
| chlorthalidone | Brand name: Thalitone Class: Thiazide diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning |
| metolazone | Brand name: Zaroxolyn Class: Thiazide diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning |
| losartan / hydrochlorothiazide | Brand name: Hyzaar Class: Combination of ARB + Thiazide diuretic Indication: Hypertension Pearls: - Take in the morning (diuretic) - Avoid in pregnancy (ARB) |
| lisinopril / hydrochlorothiazide | Brand name: Zestoretic Class: Combination of ACE-I + Thiazide diuretic Indication: Hypertension Pearls: - Take in the morning (diuretic) - Avoid in pregnancy (ACE-I) |
| furosemide | Brand name: Lasix Class: Loop diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - Can cause hypokalemia (low potassium). Many patients take a potassium supplement. |
| bumetanide | Brand name: Bumex Class: Loop diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - Can cause hypokalemia (low potassium). Many patients take a potassium supplement. |
| torsemide | Brand name: Demadex Class: Loop diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - Can cause hypokalemia (low potassium). Many patients take a potassium supplement. |
| spironolactone | Brand name: Aldactone Class: Potassium-sparing diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - Can cause hyperkalemia (high potassium) - Avoid high-potassium foods and salt substitutes like Dash |
| triamterene / hydrochlorothiazide | Brand name: Dyazide Class: Potassium-sparing diuretic + thiazide diuretic Indication: Hypertension Pearls: - Diuretics are typically taken in the morning - ADR: hyperkalemia (high potassium) - Avoid high-potassium foods / salt substitutes like Dash |
| potassium chloride | Brand name: Klor-Con; K-Dur; K-Tab Class: Potassium supplement Indication: Prevent/treat hypokalemia Pearls: - Abbreviation: KCl - Replaces potassium lost from loop/thiazides - Available as: tabs, caps, powder, solution - Solution must be diluted |
| doxazosin | Brand name: Cardura Class: Alpha 1 blocker Indication: Hypertension; BPH Pearls: - ADR: Orthostatic hypotension. Patients should rise slowly from sitting or lying positions - Alpha 1 blockers can treat HTN, BPH, or both. Doxazosin treats both. |
| terazosin | Brand name: Hytrin Class: Alpha 1 blocker Indication: Hypertension; BPH Pearls: - ADR: Orthostatic hypotension. Patients should rise slowly from sitting or lying positions - Alpha 1 blockers can treat HTN, BPH, or both. Terazosin treats both. |
| prazosin | Brand name: Minipress Class: Alpha 1 blocker Indication: Hypertension Pearls: - ADR: Orthostatic hypotension. Patients should rise slowly from sitting/lying positions - Alpha 1 blockers can treat HTN, BPH, or both. Prazosin treats HTN only. |
| tamsulosin | Brand name: Flomax Class: Alpha 1 blocker Indication: BPH Pearls: - ADR: Orthostatic hypotension. Patients should rise slowly from sitting or lying positions - Alpha 1 blockers can treat HTN, BPH, or both. Tamsulosin treats BPH only. |
| hydralazine | Brand name: Apresoline Class: Peripheral vasodilator Indication: Hypertension Pearls: - ADR: orthostatic hypotension. Patients should rise slowly from sitting or lying positions |
| clonidine | Brand name: Catapress; Kapvay Class: Alpha 2 adrenergic agonist Indication: Hypertension; ADHD Pearls: - ADR: orthostatic hypotension. Patients should rise slowly from sitting or lying positions |
| aspirin | Brand name: Various Class: NSAID; Salicylate Indication: Antiplatelet (low dose); Analgesic/antipyretic (high dose) Pearls: - Low-dose "baby aspirin" should never be given to infants - ADR: Increased bleeding risk - Abbreviation: ASA |
| clopidogrel | Brand name: Plavix Class: Antiplatelet Indication: Prevent blood clots Pearls: - ADR: Increased risk of bleeding |
| ticagrelor | Brand name: Brilinta Class: Antiplatelet Indication: Prevent blood clots Pearls: - ADR: Increased risk of bleeding |
| warfarin | Brand: Coumadin Class: Anticoagulant Indication: Prevent/treat clots Pearls: - Boxed warning: Risk of bleeding - Maintain consistent vitamin K intake - Antidote: Vitamin K (phytonadione) - Hazardous drug - Frequent blood monitoring / dose changes |
| apixaban | Brand name: Eliquis Class: Anticoagulant Indication: Prevent/treat blood clots Pearls: - ADR: Increased risk of bleeding |
| dabigatran | Brand name: Pradaxa Class: Anticoagulant Indication: Prevent/treat blood clots Pearls: - ADR: Increased risk of bleeding |
| enoxaparin | Brand name: Lovenox Class: Anticoagulant Indication: Prevent/treat blood clots Pearls: - ADR: Increased risk of bleeding - Administered via injection |
| rivaroxaban | Brand name: Xarelto Class: Anticoagulant Indication: Prevent/treat blood clots Pearls: - ADR: Increased risk of bleeding |
| nitroglycerin sublingual | Brand name: Nitro-Quick; Nitro-Stat Class: Vasodilator Indication: Angina Pearls: - SL tablet or spray. - Use 1 dose q 5 min PRN for up to 3 doses. Call 911 if no relief - DDI: PDE5-inhibitors (sildenafil, tadalafil) - Store in original container |
| isosorbide / hydralazine | Brand name: BiDil Class: Vasodilator Indication: Prevents angina (heart pain) Pearls: - DDI: PDE5-inhibitors (sildenafil, tadalafil etc.) Administering together may lead to heart attack or stroke. |
| digoxin | Brand name: Lanoxin; Digitek Class: Cardiac glycoside Indication: Heart failure; arrhythmia Pearls: - Narrow therapeutic index drug |
| atorvastatin | Brand name: Lipitor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| rosuvastatin | Brand name: Crestor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| simvastatin | Brand name: Zocor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| pravastatin | Brand name: Pravachol Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| lovastatin | Brand name: Mevacor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| ezetimibe | Brand name: Zetia Class: Antilipemic agent Indication: Hypercholesterolemia (high cholesterol) Pearls: - Decreases cholesterol absorption in the intestine - Often used with a statin |
| fenofibrate | Brand name: Tricor; Trilipix Class: Fibrate Indication: Hypercholesterolemia (high cholesterol) Pearls: - Increased risk of muscle toxicity when combined with statins |
| gemfibrozil | Brand name: Lopid Class: Fibrate Indication: Hypercholesterolemia (high cholesterol) Pearls: - Increased risk of muscle toxicity when combined with statins |
| Niacin | Brand name: Niaspan Class: Antilipemic agent Indication: Hypercholesterolemia Pearls: - Also known as vitamin B3 or nicotinic acid - ADR: Flushing - temporary and harmless. Taking aspirin can help reduce it. - Also available in OTC formulations |
| omega-3 fatty acids | Brand name: Lovaza Class: Antilipemic agent Indication: Hypercholesterolemia (high cholesterol) Pearls: - Available in OTC and Rx formulations |
| albuterol inhaler | Brand name: ProAir; Ventolin; Proventil Class: SABA (Short-acting beta agonist) Indication: Bronchospasm Pearls: - Albuterol MDIs (metered-dose inhalers) are commonly referred to as "rescue inhalers" - ADR: Increased heart rate; palpitations |
| levalbuterol inhaler | Brand name: Xopenex Class: SABA (Short-acting beta agonist) Indication: Bronchospasm Pearls: - Levalbuterol MDIs (metered-dose inhalers) are commonly referred to as "rescue inhalers" - ADR: Increased heart rate; palpitations |
| albuterol nebulizer solution | Brand name: N/A Class: SABA (Short-acting beta agonist) Indication: Bronchospasm Pearls: - Must be administered using a nebulizer - ADR: Increased heart rate; palpitations |
| fluticasone inhaler | Brand name: Flovent Class: ICS (Inhaled corticosteroid) Indication: Asthma maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush) |
| beclomethasone | Brand name: Qvar Class: ICS (Inhaled corticosteroid) Indication: Asthma maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush) |
| tiotropium | Brand name: Spiriva Class: LAMA (Long-acting muscarinic agent) Indication: Asthma/COPD maintenance Pearls: |
| umeclidinium | Brand name: Incruse Class: LAMA (Long-acting muscarinic agent) Indication: Asthma/COPD maintenance Pearls: |
| salmeterol | Brand name: Serevent Class: LABA (Long-acting beta agonist) Indication: Asthma/COPD maintenance Pearls: |
| formoterol / budesonide | Brand name: Symbicort Class: LABA / ICS Indication: Asthma/COPD maintenance and/or rescue Pearls: - Can be used for SMART therapy (single maintenance and reliever inhaler) - Rinse mouth after ICS use (prevents oral thrush) |
| salmeterol / fluticasone | Brand name: Advair Class: LABA / ICS Indication: Asthma/COPD maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush) |
| vilanterol / fluticasone | Brand name: Breo Ellipta Class: LABA / ICS Indication: Asthma/COPD maintenance Pearls: |
| formoterol / mometasone | Brand name: Dulera Class: LABA / ICS Indication: Asthma/COPD maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush) |
| vilanterol / umeclidinium | Brand name: Anoro Ellipta Class: LABA / LAMA Indication: Asthma/COPD maintenance Pearls: |
| vilanterol / umeclidinium / fluticasone | Brand name: Trelegy Ellipta Class: LABA / LAMA / ICS Indication: Asthma/COPD maintenance Pearls: - Rinse mouth after ICS use (prevents oral thrush) |
| montelukast | Brand name: Singulair Class: Leukotriene-receptor antagonist Indication: Asthma maintenance; allergy management Pearls: - Boxed warning: Neuropsychiatric events (e.g., depression, suicidal thoughts). More common during initiation and dosage changes. |
| nicotine patches | Brand name: Nicoderm Class: NRT (nicotine replacement therapy) Indication: Smoking cessation Pearls: - Available OTC - Apply to clean, dry skin; rotate sites daily |
| nicotine gum | Brand name: Nicorette Gum Class: NRT (nicotine replacement therapy) Indication: Smoking cessation Pearls: - Available OTC - Patients should use the "chew-and-park" method |
| nicotine lozenge | Brand name: Nicorette Lozenge Class: NRT (nicotine replacement therapy) Indication: Smoking cessation Pearls: - Available OTC - Allow to dissolve in mouth. Do not chew or swallow whole. |
| varenicline | Brand name: Chantix Class: Nicotinic receptor agonist Indication: Smoking cessation Pearls: - Prescription only |
| bupropion SR | Brand name: Zyban; Wellbutrin Class: Norepinephrine/dopamine reuptake inhibitor Indication: Antidepressant; smoking cessation; ADHD Pearls: - IR and ER (Wellbutrin, Wellbutrin XL) used for depression/ADHD - SR (Zyban) used for smoking cessation |
| levothyroxine | Brand name: Synthroid; Levoxyl Class: Thyroid hormone replacement Indication: Hypothyroidism (low levels of thyroid hormone) Pearls: - Narrow therapeutic index drug (NTI) - Take on an empty stomach, same time daily |
| epinephrine injector | Brand name: EpiPen Class: Sympathomimetic Indication: Anaphylaxis Pearls: - Emergency rescue injection for severe allergic reactions |
| testosterone injection | Brand name: Depo-testosterone Class: Androgen Indication: Male hypogonadism Pearls: - Injectable testosterone replacement - DEA Schedule III |
| testosterone gel | Brand name: Androgel Class: Androgen Indication: Male hypogonadism Pearls: - Topical testosterone replacement - DEA Schedule III - Risk of accidental transfer. Avoid direct skin contact with women/children. Apply to covered areas |
| conjugated estrogens | Brand name: Premarin Class: Estrogen Indication: Menopausal symptom relief Pearls: - Hormone replacement therapy (HRT) |
| oral contraceptives | Brand name: Various Class: Hormones Indication: Birth control Pearls: May contain a combination of many hormones, including: estradiol, levonorgestrel, norgestimate, norethindrone, drospirenone, and progesterone. |