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09 - Pharmacotherapy

Module 9 Pharmacotherapy

Generic nameDrug overview
insulin lispro Brand name: Humalog Class: Rapid-acting insulin Indication: Diabetes mellitus Pearls: - Rapid-acting mealtime insulin; inject right before meals - Unopened vials/pens: refrigerate 36°F–46°F (2°C–8°C) - Room-temperature BUD: 28 days once opened
insulin aspart Brand name: Novolog Class: Rapid-acting insulin Indication: Diabetes mellitus Pearls: - Meal-time insulin - Unopened vials/pens: refrigerate 36°F–46°F (2°C–8°C) - Room-temperature BUD: 28 days once opened
insulin regular Brand name: Humulin R; Novolin R Class: Short-acting insulin Indication: Diabetes mellitus Pearls: - Unopened vials/pens: refrigerate 36°F–46°F (2°C–8°C) - Room-temp BUD: Humulin R 31 days; Novolin R 42 days once opened
insulin isophane (NPH) Brand name: Humulin N; Novolin N Class: Intermediate-acting insulin Indication: Diabetes mellitus Pearls: - Cloudy appearance - Unopened vials/pens: refrigerate 36°F–46°F (2°C–8°C) - Room-temp BUD: Humulin N 31 days; Novolin N 42 days once opened
insulin glargine Brand name: Lantus; Basaglar; Toujeo Class: Long-acting insulin Indication: Diabetes Pearls: - Basal insulin; usually dosed once daily - Unopened vials/pens: refrigerate 36°F–46°F (2°C–8°C) - Room-temp BUD: Lantus & Basaglar 28 days; Toujeo 56 days
insulin detemir Brand name: Levemir Class: Long-acting insulin Indication: Diabetes mellitus Pearls: - Basal insulin - Usually dosed 1-2 times daily - Unopened vials/pens: refrigerate 36°F–46°F (2°C–8°C) - Room-temperature BUD: 42 days once opened
insulin degludec Brand name: Tresiba Class: Long-acting insulin Indication: Diabetes mellitus Pearls: - Basal insulin - Usually dosed once daily - Unopened vials/pens: refrigerate 36°F–46°F (2°C–8°C) - Room-temperature BUD: 56 days once opened
insulin lispro protamine / insulin lispro 75/25 Brand name: Humalog Mix 75/25 Class: Combination insulin Indication: Diabetes mellitus Pearls: - Contains basal + mealtime insulin - Unopened insulin vials or pens must be stored in the refrigerator at 36°F–46°F (2°C–8°C)
insulin lispro protamine / insulin lispro 50/50 Brand name: Humalog Mix 50/50 Class: Combination insulin Indication: Diabetes mellitus Pearls: - Contains basal + mealtime insulin - Unopened insulin vials or pens must be stored in the refrigerator at 36°F–46°F (2°C–8°C)
insulin NPH / insulin regular 70/30 Brand name: Novolin 70/30 Class: Combination insulin Indication: Diabetes mellitus Pearls: - Contains basal + mealtime insulin - Unopened insulin vials or pens must be stored in the refrigerator at 36°F–46°F (2°C–8°C)
insulin aspart protamine / insulin aspart 70/30 Brand name: Novolog 70/30 Class: Combination insulin Indication: Diabetes mellitus Pearls: - Contains basal + mealtime insulin - Unopened insulin vials or pens must be stored in the refrigerator at 36°F–46°F (2°C–8°C)
metformin Brand name: Glucophage Class: Biguanide Indication: Diabetes mellitus - Type 2 Pearls: - First-line therapy for type 2 diabetes - ADR: Nausea, diarrhea, abdominal discomfort
glipizide Brand name: Glucotrol Class: Sulfonylurea Indication: Diabetes mellitus - Type 2 Pearls: - ADR: Hypoglycemia (low blood sugar) - Take with a meal to minimize risk of hypoglycemia
glyburide Brand name: Diabeta Class: Sulfonylurea Indication: Diabetes mellitus - Type 2 Pearls: - ADR: Hypoglycemia (low blood sugar) - Take with a meal to minimize risk of hypoglycemia
glimepiride Brand name: Amaryl Class: Sulfonylurea Indication: Diabetes mellitus - Type 2 Pearls: - ADR: Hypoglycemia (low blood sugar) - Take with a meal to minimize risk of hypoglycemia
empagliflozin Brand name: Jardiance Class: SGLT-2 Inhibitor Indication: Diabetes mellitus - Type 2 Pearls: - Cause glucose to be excreted in urine - ADR: UTI (urinary tract infection)
canagliflozin Brand name: Invokana Class: SGLT-2 Inhibitor Indication: Diabetes mellitus - Type 2 Pearls: - Cause glucose to be excreted in urine - ADR: UTI (urinary tract infection)
dapagliflozin Brand name: Farxiga Class: SGLT-2 Inhibitor Indication: Diabetes mellitus - Type 2 Pearls: - Cause glucose to be excreted in urine - ADR: UTI (urinary tract infection)
sitagliptin Brand name: Januvia Class: DPP-4 inhibitor Indication: Diabetes mellitus - Type 2 Pearls: - Low risk of hypoglycemia
linagliptin Brand name: Tradjenta Class: DPP-4 inhibitor Indication: Diabetes mellitus - Type 2 Pearls: - Low risk of hypoglycemia
saxagliptin Brand name: Onglyza Class: DPP-4 inhibitor Indication: Diabetes mellitus - Type 2 Pearls: - Low risk of hypoglycemia
liraglutide Brand name: Victoza Class: GLP-1 agonist Indication: Diabetes mellitus - Type 2 Pearls: - Daily injection - Stored in the refrigerator at temperatures between 36°F and 46°F (2°C to 8°C) - May aid in weight loss - ADR: Nausea
semaglutide Brand name: Ozempic; Rybelsus Class: GLP-1 agonist Indication: Type 2 diabetes Pearls: - Ozempic = once-weekly injection. Refrigerate at 36°F to 46°F (2°C to 8°C) - Rybelsus = daily tablet. Store at room temp. - May aid in weight loss - ADR: Nausea
dulaglutide Brand name: Trulicity Class: GLP-1 agonist Indication: Diabetes mellitus - Type 2 Pearls: - Once-weekly injection - Stored in the refrigerator at temperatures between 36°F and 46°F (2°C to 8°C) - May aid in weight loss - ADR: Nausea
Created by: pta78
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