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02 - Pharmacotherapy
Module 2 Pharmacotherapy
| Generic name | Drug overview |
|---|---|
| atorvastatin | Brand name: Lipitor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| rosuvastatin | Brand name: Crestor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| simvastatin | Brand name: Zocor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| pravastatin | Brand name: Pravachol Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| lovastatin | Brand name: Mevacor Class: HMG-CoA reductase inhibitor (statin) Indication: Hypercholesterolemia Pearls: - Statins interact with grapefruit. Do not eat grapefruit or drink grapefruit juice. - ADR: Muscle pain, weakness, or cramps; rhabdomyolysis. |
| ezetimibe | Brand name: Zetia Class: Antilipemic agent Indication: Hypercholesterolemia (high cholesterol) Pearls: - Decreases cholesterol absorption in the intestine - Often used with a statin |
| fenofibrate | Brand name: Tricor; Trilipix Class: Fibrate Indication: Hypercholesterolemia (high cholesterol) Pearls: - Increased risk of muscle toxicity when combined with statins |
| gemfibrozil | Brand name: Lopid Class: Fibrate Indication: Hypercholesterolemia (high cholesterol) Pearls: - Increased risk of muscle toxicity when combined with statins |
| Niacin | Brand name: Niaspan Class: Antilipemic agent Indication: Hypercholesterolemia Pearls: - Also known as vitamin B3 or nicotinic acid - ADR: Flushing - temporary and harmless. Taking aspirin can help reduce it. - Also available in OTC formulations |
| omega-3 fatty acids | Brand name: Lovaza Class: Antilipemic agent Indication: Hypercholesterolemia (high cholesterol) Pearls: - Available in OTC and Rx formulations |