Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
autonomic drugs UCI
| Question | Answer |
|---|---|
| epinephrine | a1, a2, b2, b3, low doses selective for b1; anaphylaxis, glaucoma, asthma, hypotension |
| NE | a1, a2>b1; hypotenstion with decreased renal perusion |
| Isoproterenol | b1=b2; AV block |
| Dopamine | D1=D2>b>a, inotropic and chronotropic; shock, heart failure |
| Dobutamine | b1>b2, inotropic not chronotropic; shock, heart failure, cardiac stress testing |
| Phenylephrine | =methoxamine, a1>a2; pupillary dilation, vasoconstriction, nasal congestion |
| Methoxamin | =phenylephrine; a1>a2; pupillary dilation, vasoconstriction, nasal congestion |
| Albuterol | b2>b1; acute asthma |
| terbutaline | b2>b1; reduces premature uterine contractions |
| ritodrine | =metaproterenol; b2 reduces premature uterine contractions |
| metaproterenol | =ritodrine; b2 reduces premature uterine contractions |
| amphetamine | releases stored catecholamines; narcolepsy, obesity, ADD |
| ephedrine | =tyramine; releases stored catecholamines; nasal decongestion, urinary incontinence, hypotension |
| tyramine | =ephedrine; releases stored catecholamines; nasal decongestion, urinary incontinence, hypotension |
| cocaine | uptake inhibitor; causes vasoconstriction and local anesthesia |
| clonadine | =a-methyldopa; a2 agonist; hypertension with renal disease (no decrease in renal blood flow), glaucoma, sedation |
| a-methyldopa | =clonadine; a2 agonist; hypertension with renal disease (no decrease in renal blood flow) |
| guanfacine | =clonidine, brimonidine, dexmadetomidine; a2 agonist; hypertension with renal disease (no decrease in renal blood flow), glaucoma, sedation |
| brimonidine | =clonidine, guanficine, dexmedetomidine; a2 agonist; hypertension with renal disease (no decrease in renal blood flow), glaucoma, sedation |
| dexmedetomidine | =clonidine, guanfacine, brimonidine; a2 agonist; hypertension with renal disease (no decrease in renal blood flow), glaucoma, sedation |
| b2 agonists | MAST; metaproterenol, albuterol, salmeterol, terbutaline |
| phenoxybenzamine | irreversible a-blocker; for pheochromocytoma tumor removal; toxic-orthostatic hypotenstion, reflex tachycardia |
| phentolamine | reversible a-blocker; for pheochromocytoma tumor removal; toxic-orthostatic hypotenstion, reflex tachycardia |
| prazosin | =terazosin, doxazosin;a1-blocker; for htn, urinary retention in BPH; toxic-orthostatic hypotenstion, dizziness, headache, cardiac problems |
| terazosin | =prazosin, doxazosin; a1-blocker; for htn, urinary retention in BPH; toxic-orthostatic hypotenstion, dizziness, headache, cardiac problems |
| doxazosin | =prazosin, terazosin; a1-blocker; for htn, urinary retention in BPH; toxic-orthostatic hypotenstion, dizziness, headache, cardiac problems |
| mirtazapine | a2 blocker; for depression; toxic- sedation, increased serum cholesterol and appetite |
| nonselective b-blockers | propranolol, timolol, nadolol, pindolol, labetalol |
| b1 blockers | A BEAM; acebutolol, betaxolol, esmolol, atenolol, metoprolol |
| b blocker application | HTN (lower CO ad renin), angina pectoris, thyroid storm, migraine, anxiety, MI, SVT, CHF, glaucoma (decreased secretion |
| b blocker toxicity | impotence, worse asthma, CV problems, hypoglycemia, b-receptor hypersensitivity, sedation, sleep alterations |
| a-methyl-para-tyrosine | inhibits tyrosine hydroxylase |
| reserpine | binds VMAT 1+2 depleting catecholamine stores (obsolete) |
| tetrabenzine | binds VMAT 2 (for Huntington’s chorea) |
| guanethidine | displaces NE in storage granules; no BBB; receptor hypersensitivity; for HTN |
| imipramine | =amitryptiline; potentiate direct acting, inhibit indirect acting sympatomimetics |
| amitryptiline | =imipramine; potentiate direct acting, inhibit indirect acting sympatomimetics |
| isocarboxiazide | ==tranylcypromine; MAO inhibitor, for depression and parkinson's |
| tranylcypromine | =isocarboxiazide; MAO inhibitor, for depression and parkinson's |
| cevimeline | =pilocarpine; cholinomimetic; stimulates sweat, tears, saliva; used for glaucoma among others |
| methacholine | asthma challenge test; cholinomimetic |
| neostigmine | anticholinesterase; postoperative and neurogenic ileus and urinary retention, myesthenia gravis, reversal of neuromuscular junction blockade |
| pyridostigmine | =ambenonium; myasthenia gravis |
| ambenonium | =pyridostigmine; myasthenia gravis |
| edrophonium | diagnose myasthenia gravis |
| physostigmine | glaucoma and atropine overdose and to increase bowel/bladder motility |
| echothiophate | irreversible anticholinesterase; glaucoma |
| galantamine | =rivastigmine, donepazil, tacrine; anticholinesterase; alzheimer 1st line |
| rivastigmine | =galantamine, donepazil, tacrine; anticholinesterase; alzheimer 1st line |
| donepazil | =galantamine, rivastigmine, tacrine; anticholinesterase; alzheimer 1st line |
| tacrine | =galantamine, rivastigmine, donepazil; anticholinesterase; alzheimer 1st line |
| cholinesterase inhibitor poisoning | DUMBBELSS: diarrhea, urination, miosis, bronchospas, bradycardia, excitation of skeletal muscle and CNS, lacrimation, sweating, salivation |
| antidote to anticholinesterase poisoning | atropine plus pralidoxime (ZPAM) |
| parathion | =malathione; insectiside and anticholinesterase |
| malathione | =parathione; insectiside and anticholinesterase |
| isofluorophate (DFP) | anticholinesterase; inactivates AchE for days to weeks by phosphorylation |
| atropine | =homatropine, tropicamide; produce mydriasis and cycloplegia; blocks DUMBBELSS |
| homatropine | =atropine, tropicamine; produce mydriasis and cycloplegia |
| tropicamine | = atroopine, homatropine; produce mydriasis and cycloplegia |
| benztropine | muscarinic antogonist; parkinson's |
| scopalamine | muscarinic antagonist; motion sickness and short term memory loss |
| ipratropium | =tiotropium; asthma, COPD; muscarinic antagonist |
| triotropium | =ipratropium; asthma, COPD; muscarinic antagonist |
| oxybutynin | =glycopyrrolate, clidum; muscarinic antagonist; reduce urgency in cystitis and reduce bladder spasms |
| glycopyrrolate | =oxybutynin, clidium; muscarinic antagonist; reduce urgency in cystits and reduce bladder spasms |
| clidium | =oxybutynin, glycopyrrolate; muscarinic antagonist; reduce urgency in cystitis and reduce bladder spasms |
| tolterodine | urinary incontinence in elderly; enuresis in kids; muscarinic antagonist |
| methscopalamine | =pirenzepine, propantheline; muscarinic antagonist; peptic ulcer treatment |
| pirenzepine | =methscopalamine, propantheline; muscarinic antagonist; peptic ulcer treatments |
| propantheline | =methscopalamine, pirenzepine; muscarinic antagonist; peptic ulcer treatments |
| hexamethonium | nicotinic antagonist |
Created by:
droid
Popular Pharmacology sets