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BDK Endocrine #2-3
Basic Drug Knowledge Endocrine Page #2-3
| Generic Name | Brand Name | Classification | Pharmacologic Category | Common Indications | Key Side Effects | US Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|---|
| Drospirenone & Ethinyl Estradiol (PO) | Yasmin 28, Yaz | Contraceptive | Contraception, Acne | Nausea, Changes in Menstrual Flow, Breast Tenderness, Thromboembolic Disorders, Headache, Weight Gain | Increased risk of cardiovascular events in women > 35 years old who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, & cardiovascular disease | |
| Levonorgestrel & Ethinyl Estradiol (PO) | Lutera, Levora, Seasonique | Contraceptive | Contraception, Acne | Nausea, Changes in Menstrual Flow, Breast Tenderness, Thromboembolic Disorders, Headache, Weight Gain | Increased risk of cardiovascular events in women > 35 years old who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, & cardiovascular disease | |
| Norethindrone & Ethinyl Estradiol (PO) | Junel, Loestrin, Microgestin | Contraceptive | Contraception, Acne | Nausea, Changes in Menstrual Flow, Breast Tenderness, Thromboembolic Disorders, Headache, Weight Gain | Increased risk of cardiovascular events in women > 35 years old who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, & cardiovascular disease | |
| Norethindrone, Ethinyl Estradiol, & Ferrous Fumarate (PO) | Lo Loestrin Fe, Microgestin Fe | Contraceptive | Contraception, Acne | Nausea, Changes in Menstrual Flow, Breast Tenderness, Thromboembolic Disorders, Headache, Weight Gain | Increased risk of cardiovascular events in women > 35 years old who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, & cardiovascular disease | |
| Norgestimate & Ethinyl Estradiol (PO) | Tri-Sprintec, Sprintec | Contraceptive | Contraception, Acne | Nausea, Changes in Menstrual Flow, Breast Tenderness, Thromboembolic Disorders, Headache, Weight Gain | Increased risk of cardiovascular events in women > 35 years old who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, & cardiovascular disease | |
| Norgestrel & Ethinyl Estradiol (PO) | Crysell-28, Low-Ogestrel | Contraceptive | Contraception, Acne | Nausea, Changes in Menstrual Flow, Breast Tenderness, Thromboembolic Disorders, Headache, Weight Gain | Increased risk of cardiovascular events in women > 35 years old who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, & cardiovascular disease | |
| Estrogens, Conjugated (Equine) (PO, Topical) | Premarin | Estrogen Derivative | Vasomotor Symptoms Associated with Menopause, Vaginal Atrophy Associated with Menopause | Irritation at Application Site (Transdermal Patch Only), Edema, Abdominal Pain, Breast Tenderness, Weight Gain, Thromboembolic disorders (Myocardial Infarction, Stroke, VTE) | Increased risk of breast cancer; Should not be used for dementia prevention; Increased risk of endometrial cancer if not used concomitantly with progestin in women with a uterus; Should not be used for prevention of cardiovascular disease | CI in hepatic dysfunction, thromboembolic disorders, cardiovascular disease, breast cancer, & estrogen-dependent tumor | |
| Estradiol (Transdermal, PO) | Transdermal: Climara, Vivelle Dot PO: Estrace | Estrogen Derivative | Vasomotor Symptoms Associated with Menopause, Vaginal Atrophy Associated with Menopause | Irritation at Application Site (Transdermal Patch Only), Edema, Abdominal Pain, Breast Tenderness, Weight Gain, Thromboembolic disorders (Myocardial Infarction, Stroke, VTE) | Increased risk of breast cancer; Should not be used for dementia prevention; Increased risk of endometrial cancer if not used concomitantly with progestin in women with a uterus; Should not be used for prevention of cardiovascular disease | CI in hepatic dysfunction, thromboembolic disorders, cardiovascular disease, breast cancer, & estrogen-dependent tumor | |
| Medroxyprogesterone (PO) | Provera | Progestin | Abnormal Uterine Bleeding, Secondary Amenorrhea | Acne, Abnormal Menstrual Bleeding, Headache, Amenorrhea, Weight Gain | Increased risk of breast cancer; Should not be used for dementia prevention; Should not be used for prevention of cardiovascular disease | CI in thromboembolic disorders, cardiovascular disease, estrogen or progesterone-dependent tumors, undiagnosed abnormal genital bleeding, hepatic impairment | |
| Testosterone Gel (Topical) | AndroGel, Fortesta, Vogelxo | CS-III | Androgen | Male Hypogonadism | Contact Dermatitis, Acne, Increased Prostate Specific Antigen (PSA), Emotional Lability, Hypertension | Secondary exposure may result in virilization (especially in children) | CI in males iwth breast or prostate cancer and pregnant women; Apply in the morning |
| Alendronate (PO) | Fosamax | Bisphosphonate | Osteoporosis | Dyspepsia, Gastroesophageal Reflux Disease, Hypocalcemia, Atypical Fractures, Osteonecrosis of the Jaw | CI in patients with hypocalcemia or abnormalities of the esophagus; Administer ≥ 30 minutes before food or drink (except plain water); Remain upright for 30 minutes following dose to reduce esophageal irritation | ||
| Cholecalciferol (Vitamin D3) (PO) | --- | OTC | Vitamin D Analog | Dietary Supplement, Osteoporosis Prevention | Vitamin D Toxicity (Nausea, Vomiting, Loss of Appetite, Constipation, Confusion, Weakness) | CI with hypercalcemia | |
| Sildenafil (PO) | Viagra, Revatio | Phosphodiesterase-5 Enzyme (PDE5) Inhibitor | Erectile Dysfunction (ED), Pulmonary Arterial Hypertension (PAH) | Priapism, Headache, Flushing, Visual Disturbance, Dyspepsia, Back Pain (Mostly with Tadalafil), Hearing or Vision Loss (Rare) | CI with concomitant use of nitrates (may cause severe hypotension) | ||
| Tadalafil (PO) | Cialis, Adcirca | Phosphodiesterase-5 Enzyme (PDE5) Inhibitor | Erectile Dysfunction (ED), Benign Prostatic Hyperplasia (BPH), Pulmonary Arterial Hypertension (PAH) | Priapism, Headache, Flushing, Visual Disturbance, Dyspepsia, Back Pain (Mostly with Tadalafil), Hearing or Vision Loss (Rare) | CI with concomitant use of nitrates (may cause severe hypotension) | ||
| Levothyroxine (PO) | Synthroid, Levoxyl, Unithroid | Thyroid Product | Hypothyroidism | Weight Loss, Palpitations, Diarrhea, Insomnia, Heat Intolerance | Not intended for use for weight loss | Narrow therapeutic index drug (therapeutic monitoring is recommended); Not all generic products are therapeutically equivalent | |
| Thyroid, Desiccated (PO) | Armour Thyroid | Thyroid Product | Hypothyroidism | Weight Loss, Palpitations, Diarrhea, Insomnia, Heat Intolerance | Not intended for use for weight loss | Narrow therapeutic index drug (therapeutic monitoring is recommended); Not all generic products are therapeutically equivalent | |
| Phentermine (PO) | Adipex-P | CS-IV | CNS Stimulant, Anorexiant | Short Term Weight Management | Tachycardia, Hypertension, Nausea, Dizziness, Xerostomia, Agitation | Only approved for short-term use up to 12 weeks; CI in those with a history of cardiovascular disease or drug abuse, pregnancy, hyperthyroidism, or within 14 days of MAOI (Monoamine Oxidase Inhibitor) therapy |
Created by:
nataliemvo
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