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BDK Endocrine #1

Basic Drug Knowledge Endocrine Page #1

Generic NameBrand NameClassificationPharmacologic CategoryCommon IndicationsKey Side EffectsUS Boxed WarningsOther Notes
Metformin (PO) Fortamet, Glumetza, Riomet Biguanide Type 2 Diabetes Mellitus (DM), Polycystic Ovarian Syndrome (PCOS) Diarrhea, Nausea, Vomiting, Vitamin B12 Deficiency Lactic Acidosis CI with eGFR <30
Sitagliptin (PO) Januvia, Zituvio Dipeptidyl Peptidase (DPP-4) Inhibitor Type 2 Diabetes Mellitus (DM) Nasopharyngitis
Empagliflozin (PO) Jardiance Sodium-Glucose Cotransporter Inhibitor 2 (SGLT2 Inhibitor) Type 2 Diabetes Mellitus (DM), Heart Failure (HF), Chronic Kidney Disease (CKD) Genital Mycotic Infections, UTI
Dapagliflozin (PO) Farxiga Sodium-Glucose Cotransporter Inhibitor 2 (SGLT2 Inhibitor) Type 2 Diabetes Mellitus (DM), Heart Failure (HF), Chronic Kidney Disease (CKD) Genital Mycotic Infections, UTI
Glimepiride (PO) Amaryl Sulfonylurea Type 2 Diabetes Mellitus (DM) Hypoglycemia, Weight Gain
Glipizide (PO) Glucotrol, Glucotrol XL Sulfonylurea Type 2 Diabetes Mellitus (DM) Hypoglycemia, Weight Gain
Pioglitazone (PO) Actos Thiazolidinedione (TZD) Type 2 Diabetes Mellitus (DM) Peripheral Edema, Weight Gain, Upper Respiratory Tract Infection; Increased Risk of Fratures & Bladder Cancer May exacerbate congestive heart failure & CI in NYHA Class III & IV
Dulaglutide (SQ) Trulicity Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Type 2 Diabetes Mellitus (DM) Nausea, Vomiting, Diarrhea, Pancreatitis May increase risk of thyroid c-cell tumor, CI in personal or family history of medullary thyroid cancer & in patients with multiple endocrine neoplasia syndrome type 2
Liraglutide (SQ) Victoza, Saxenda Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Type 2 Diabetes Mellitus (DM), Chronic Weight Management Nausea, Vomiting, Diarrhea, Constipation, Pancreatitis May increase risk of thyroid c-cell tumor, CI in personal or family history of medullary thyroid cancer & in patients with multiple endocrine neoplasia syndrome type 2
Semaglutide (PO, SQ) SQ: Ozempic, Wegovy PO: Rybelsus, Wegovy Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Type 2 Diabetes Mellitus (DM), Chronic Weight Management Nausea, Vomiting, Diarrhea, Constipation, Pancreatitis May increase risk of thyroid c-cell tumor, CI in personal or family history of medullary thyroid cancer & in patients with multiple endocrine neoplasia syndrome type 2
Tirzepatide (SQ) Mounjaro, Zepbound Dual GLP-1 and Glucose-Dependent Insulinotropic Polypeptide (GIP) Agonist Type 2 Diabetes Mellitus (DM), Chronic Weight Management Nausea, Vomiting, Diarrhea, Constipation, Increased Heart Rate, Pancreatitis May increase risk of thyroid c-cell tumor, CI in personal or family history of medullary thyroid cancer & in patients with multiple endocrine neoplasia syndrome type 2
Insulin Glargine (SQ) Lantus, Toujeo, Basaglar Insulin, Long Acting Type 1 Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (DM) Hypoglycemia, Weight Gain
Insulin NPH (SQ) Humulin N, Novolin N OTC Insulin, Intermediate Acting Type 1 Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (DM) Hypoglycemia, Weight Gain
Insulin Aspart (SQ) Novolog, Fiasp Insulin, Rapid Acting Type 1 Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (DM) Hypoglycemia, Weight Gain
Insulin Lispro (SQ) Humalog, Admelog, Lyumjev Insulin, Rapid Acting Type 1 Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (DM) Hypoglycemia, Weight Gain
Insulin Regular (SQ, IV) Humulin R, Novolin R SQ: OTC Insulin, Short-Acting Type 1 Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (DM), Diabetic Ketoacidosis (DKA) Hypoglycemia, Weight Gain
Created by: nataliemvo
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