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DEENT 2
| Category | Generic | Brand | Indication | EK |
|---|---|---|---|---|
| Alpha (α1) agonist | pseudoephedrine (PO) | Sudafed | Nasal congestion | Key Side Effects: Increased blood pressure, tachycardia, palpitations, insomnia, restlessness Other notes: sold behind the counter, avoid during first trimester of pregnancy |
| Corticosteroid | fluticasone (intranasal) | Flonase | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| Corticosteroid | triamcinolone (intranasal) | Nasacort | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| Histamine (H1) blocker | azelastine (intranasal) | Astepro | Allergic rhinitis | Key Side Effects: headache, nasal dryness, epistaxis, bitter taste, drowsiness |
| Histamine (H1) blocker | diphenhydramine (PO, IV) | Benadryl | Allergic rhinitis, allergic reaction, insomnia | Key Side Effects: drowsiness, constipation, xerostomia, urinary retention, cognitive impairment Other Notes: for OTC use, do NOT use in children < 6 years of age |
| Histamine (H1) blocker | hydroxyzine (PO, IV) | Atarax, Vistaril | Pruritus, nausea, anxiety | Key Side Effects: dizziness, somnolence, xerostomia, blurred vision, QTc prolongation |
| Histamine (H1) blocker | cetirizine (PO) | Zyrtec | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | loratadine (PO) | Claritin | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | fexofenadine (PO) | Allegra | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | levocetirizine (PO) | Xyzal | Allergic rhinitis | Key Side Effects: diarrhea, drowsiness, headache |
| Histamine (H1) blocker | olopatadine (ophthalmic) | Pataday, Patanol | Allergic conjunctivitis | Key Side Effects: ocular burning, discomfort, dryness |
| Histamine (H1) blocker and opioid analgesic | promethazine and codeine (PO) | Phenergan with Codeine | Cough | Key side effects: dizziness, somnolence, xerostomia, blurred vision, constipation, respiratory depression (dose-related). Boxed warning: opioids with benzos/CNS depressants (incl. alcohol) may cause sedation, resp. depression, coma, death. Not for <18. |
| Opioid analgesic and expectorant | codeine and guaifenesin (PO) | Robitussin AC, Cheratussin AC | Cough | Key Side Effects: dizziness, somnolence, constipation, respiratory depression (dose-related) Other Notes: opioid-containing cough and cold products no longer indicated for use in patients <18 years of age |