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Infectious Disease 3

CategoryGenericBrandIndicationActivity againstEK
Lincosamide antibiotic clindamycin (PO, IV) Cleocin SSTI, pharyngitis MRSA Key Side Effects: diarrhea, C. difficile diarrhea. US Boxed Warnings: C. difficile–associated diarrhea (CDAD) may occur with most antibiotics, including clindamycin, ranging from mild diarrhea to fatal colitis.
Sulfonamide antibiotic sulfamethoxazole and trimethoprim (PO, IV) Bactrim, Bactrim DS SSTI, cystitis, pyelonephritis, opportunistic infection prophylaxis MRSA, Enterobacteriaceae Key Side Effects: nausea, vomiting, diarrhea, skin rashes (rarely SJS or TEN), photosensitivity, crystalluria, hyperkalemia, increased serum creatinine, hypersensitivity reactions
Urinary antibiotic nitrofurantoin (PO) Macrobid Cystitis Escherichia coli Key Side Effects: nausea, pulmonary fibrosis (chronic use)
Urinary antibiotic fosfomycin (PO) Monurol Cystitis Escherichia coli Key Side Effects: headache, diarrhea, nausea
Aminoglycoside antibiotic tobramycin (IV, inhaled) Tobi (inhaled) HAP, cystic fibrosis (nebulized only) Escherichia coli, Pseudomonas aeruginosa Key Side Effects: nephrotoxicity, ototoxicity
Glycopeptide antibiotic vancomycin (IV, PO) Vancocin IV: SSTI, HAP, meningitis, endocarditis, CRBSI PO: CDI MRSA, Clostridioides difficile (PO only) Key Side Effects: nephrotoxicity, vancomycin infusion reaction, ototoxicity
Antibiotic metronidazole (PO, IV) Flagyl Anaerobic infections, CDI Bacteroides species, Clostridioides difficile Key Side Effects: nausea, metallic taste, disulfiram reaction with alcohol, peripheral neuropathy (long-term use)
Antibiotic mupirocin (topical) Bactroban MRSA decolonization Key Side Effects: no major side effects
Topical antibiotic neomycin + polymyxin B + bacitracin (topical, ophthalmic) Topical: Neosporin Ophthalmic: Neo-Polycin Topical infection prevention, Ocular infections Key Side Effects: reddening, itching
Created by: PharmacistJulian
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