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Exam 2 Pharm

QuestionAnswer
• Oxytocin (Pitocin): : Stimulates uterine contractions. Used for induction and postpartum hemorrhage. Monitor FHR and contractions closely.
• Dinoprostone (PGE : Cervical ripening agent. Used intravaginally to prepare the cervix for induction
• Misoprostol (PGE■) Off-label cervical ripening. Contraindicated after prior C-section. Monitor for uterine tachysystole.
• Terbutaline: : Beta■-agonist. Relaxes uterine smooth muscle. AE: tachycardia, tremor
• Nifedipine Calcium channel blocker. AE: hypotension, flushing.
Indomethacin NSAID that inhibits prostaglandins. Risk: ductus arteriosus closure after 32 wks.
• Magnesium sulfate: : Smooth muscle relaxant; prevents seizures and delays preterm labor. Toxicity: loss of reflexes, respiratory depression. Antidote: Calcium gluconate.
• Clomiphene citrate Stimulates ovulation via FSH/LH increase. AE: hot flashes, ovarian enlargement.
Letrozole Aromatase inhibitor. Increases FSH for ovulation. AE: dizziness, fatigue
• hMG/hCG : Stimulate ovulation. Monitor for ovarian hyperstimulation syndrome (OHSS).
• Phentermine Appetite suppressant. AE: hypertension, insomnia
• Orlistat Lipase inhibitor that blocks fat absorption. AE: steatorrhea. Take with low-fat diet and multivitamins.
• Liraglutide/Semaglutide GLP-1 agonists. Delay gastric emptying. AE: nausea. Contraindicated with thyroid tumors.
Bupropion/Naltrexone Decreases appetite and cravings. Avoid in seizure disorders
I – Na+ Blockers-Procainamide, Lidocaine, Flecainide Slow conduction; used for atrial and ventricular arrhythmias Proarrhythmia, QT prolongation, CNS eff
II – Beta Blockers- Metoprolol, Esmolol Decrease SA/AV node conduction; rate control for AFib/SVT Bradycardia, hypotension, bronchospasm
III – K+ Blockers Amiodarone, Sotalol Prolong repolarization; rhythm control Pulmonary fibrosis, thyroid/liver toxicity, QT prolon
IV – Ca2+ Blockers-Diltiazem, Verapamil Decrease AV conduction; rate controlBradycardia, hypotension, constipation
Other-Adenosine, Digoxin Adenosine for PSVT; Digoxin for HF/AFib Asystole (adenosine), digoxin toxicity (visual halos
Dobutamine : Beta■-agonist; increases cardiac output in heart failure. AE: tachyarrhythmias
• Dopamine : Dose-dependent effects (low = renal perfusion; high = vasoconstriction). AE: tachycardia
Milrinone : PDE3 inhibitor; increases contractility and vasodilation. AE: hypotension
• Digoxin : Increases contractility and vagal tone; narrow therapeutic index. Toxicity: N/V, halos, arrhythmia. Antidote: Digoxin immune Fab
Nitroglycerin Venodilation → decreased preload. AE: headache, hypotension. CI: PDE-5 inhibitors (V
• Hydralazine Direct arterial dilator. AE: reflex tachycardia, lupus-like syndrome.
Nitroprusside Arterial & venous dilation. AE: cyanide toxicity (limit use). Protect from light
• Norepinephrine Alpha■ > Beta■ agonist; used for septic shock. Monitor BP, perfusion
• Epinephrine Used in cardiac arrest & anaphylaxis.
Phenylephrine Alpha■ agonist; vasoconstriction. AE: reflex bradycardia.
Amiodarone requires lung, liver, and thyroid monitoring.
• Nitrates + PDE-5 inhibitors = contraindicated.
Stop oxytocin for tachysystole or late decelerations position laterally and give O
Magnesium sulfate toxicity = calcium gluconate antidote.
Digoxin toxicity worsens with hypokalemia monitor K■ and renal function
Created by: Anmag002
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