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Endocrine 3

Pharmacological CategoryGenericBrandClassificationCommon IndicationKey side effectsUS Boxed WarningOther notes
Androgen testosterone gel (topical) AndroGel, Fortesta, Vogelxo CS-III Male hypogonadism contact dermatitis, acne, increased prostate specific antigen (PSA), emotional lability, hypertension secondary exposure may result in virilization (especially in children) CI in males with breast or prostate cancer and pregnant women; apply in the morning
Bisphosphonate alendronate (PO) Fosamax n/a Osteoporosis dyspepsia, gastroesophageal reflux disease, hypocalcemia, atypical fractures, osteonecrosis of the jaw n/a CI in patients with hypocalcemia or abnormalities of the esophagus; administer ≥30 minutes before food or drink (except plain water); remain upright for 30 minutes following dose to reduce esophageal irritation
Vitamin D analog cholecalciferol (vitamin D3) (PO) n/a OTC Dietary supplement, osteoporosis prevention vitamin D toxicity (nausea, vomiting, loss of appetite, constipation, confusion, weakness) n/a CI with hypercalcemia
Phosphodiesterase-5 enzyme (PDE5) inhibitor sildenafil (PO) Viagra, Revatio n/a ED, PAH priapism, headache, flushing, visual disturbance, dyspepsia, back pain (mostly with tadalafil), hearing or vision loss (rare) n/a CI with concomitant use of nitrates (may cause severe hypotension)
Phosphodiesterase-5 enzyme (PDE5) inhibitor tadalafil (PO) Cialis, Adcirca n/a ED, BPH, PAH priapism, headache, flushing, visual disturbance, dyspepsia, back pain (mostly with tadalafil), hearing or vision loss (rare) n/a CI with concomitant use of nitrates (may cause severe hypotension)
Thyroid product levothyroxine (PO, IV) Synthroid, Levoxyl, Unithroid n/a Hypothyroidism weight loss, palpitations, diarrhea, insomnia, heat intolerance not intended for use for weight loss narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent
Thyroid product thyroid, desiccated (PO) Armour Thyroid n/a Hypothyroidism weight loss, palpitations, diarrhea, insomnia, heat intolerance not intended for use for weight loss narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent
CNS stimulant, anorexiant phentermine (PO) Adipex-P CS-IV Obesity tachycardia, hypertension, nausea, dizziness, xerostomia, agitation n/a only approved for short-term use; CI in those with a history of cardiovascular disease or drug abuse, pregnancy, hyperthyroidism, or within 14 days of MAOI therapy
Created by: ziad5
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