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Pain, Hema, & Onco 2

Pharmacologic Category Generic NameBrand NameClassification
Opioid and nonopioid analgesic combination hydrocodone and acetaminophen (PO) Lortab, Vicodin, Norco CS-II Pain Key Side Effects: dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression US Boxed Warnings: use with CYP3A4 inhibitors (or stopping CYP3A4 inducers) can increase oxycodone concentrations; hepatotoxicity
Opioid and nonopioid analgesic combination oxycodone and acetaminophen (PO) Percocet, Endocet CS-II Pain Key Side Effects: dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression US Boxed Warnings: use with CYP3A4 inhibitors (or stopping CYP3A4 inducers) can increase oxycodone concentrations; hepatotoxicity
Opioid and nonopioid analgesic combination codeine and acetaminophen (PO) Tylenol with Codeine #3, Tylenol with Codeine #4 CS-III Pain Key Side Effects: dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression US Boxed Warnings: concomitant use or discontinuation of CYP3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors requires careful consideration; respira
Opioid antagonist naloxone (IV, IM, SQ, intranasal) Narcan Nasal Spray, Zimhi Narcan Nasal Spray: OTC Opioid overdose Key Side Effects: opioid withdrawal syndrome in opioid-dependent populations, pain
Partial opioid agonist and opioid antagonist buprenorphine and naloxone (SL) Suboxone CS-III Opioid use disorder Key Side Effects: opioid withdrawal syndrome in opioid-dependent populations, constipation, headache, diaphoresis Other Notes: potentially life-threatening respiratory depression (when combined with other CNS and respiratory depressants); addition of na
Iron supplement ferrous sulfate (PO) FeroSul, SlowFe OTC Iron deficiency anemia Key Side Effects: nausea, stomach upset, constipation (dose-related), dark and tarry stools US Boxed Warning: accidental overdose of iron is leading cause of fatal poisoning in children under 6 years old
Water-soluble vitamin cyanocobalamin (vitamin B12 ) (PO, IM, SL, intranasal) --- PO SL OTC Vitamin B12 deficiency (manifests as macrocytic anemia) Key Side Effects: no major side effects
Water-soluble vitamin folic acid (PO) --- OTC Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy Key Side Effects: no major side effects
Created by: kimchii
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