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Neuro/Psych 1
| Generic | Brand | Category | Indication | EK |
|---|---|---|---|---|
| mirtazapine (PO) | Remeron | Alpha2 antagonist | MDD | Key Side Effects: drowsiness, weight gain, xerostomia, increased appetite, constipation US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults |
| bupropion (PO) | Wellbutrin SR, Wellbutrin XL | Norepinephrine- dopamine reuptake inhibitor | MDD | Key side effects: tachycardia, headache, agitation, dizziness, insomnia, weight loss, dry mouth. Boxed warnings: suicidal thoughts, neuropsychiatric reactions. Notes: ↑ seizure risk; CI in seizure or eating disorders. |
| atomoxetine (PO) | Strattera | Selective norepinephrine reuptake inhibitor | ADHD | Key Side Effects: hypertension, tachycardia, headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia US Boxed Warnings: increased risk of suicidal ideation in children or adolescents Other Notes: CI within 14 days of MAOI |
| desvenlafaxine (PO) | Pristiq | Serotonin- norepinephrine reuptake inhibitor (SNRI) | MDD | Key side effects: headache, dry mouth, nausea, vomiting, constipation, ↓ appetite, insomnia, sweating, HTN, sexual dysfunction. Boxed warning: ↑ risk of suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop. |
| duloxetine (PO) | Cymbalta | Serotonin- norepinephrine reuptake inhibitor (SNRI) | MDD, neuropathic pain | Key side effects: headache, dry mouth, nausea, vomiting, constipation, ↓ appetite, insomnia, sweating, HTN, sexual dysfunction. Boxed warning: ↑ risk of suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop. |
| venlafaxine (PO) | Effexor XR | Serotonin- norepinephrine reuptake inhibitor (SNRI) | MDD | Key side effects: headache, dry mouth, nausea, vomiting, constipation, ↓ appetite, insomnia, sweating, HTN, sexual dysfunction. Boxed warning: ↑ risk of suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop. |
| citalopram (PO) | Celexa | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key side effects: drowsiness, insomnia, nausea, vomiting, dry mouth, sexual dysfunction, headache, sweating. Boxed warning: ↑ suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop (except fluoxetine). |
| fluoxetine (PO) | Prozac | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key side effects: drowsiness, insomnia, nausea, vomiting, dry mouth, sexual dysfunction, headache, sweating. Boxed warning: ↑ suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop (except fluoxetine). |
| escitalopram (PO) | Lexapro | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key side effects: drowsiness, insomnia, nausea, vomiting, dry mouth, sexual dysfunction, headache, sweating. Boxed warning: ↑ suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop (except fluoxetine). |
| paroxetine (PO) | Paxil | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key side effects: drowsiness, insomnia, nausea, vomiting, dry mouth, sexual dysfunction, headache, sweating. Boxed warning: ↑ suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop (except fluoxetine). |
| sertraline (PO) | Zoloft | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key side effects: drowsiness, insomnia, nausea, vomiting, dry mouth, sexual dysfunction, headache, sweating. Boxed warning: ↑ suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop (except fluoxetine). |
| trazodone (PO) | Desyrel | Serotonin reuptake inhibitor | Insomnia, MDD | Key Side Effects: sedation, headache, dizziness, xerostomia, nausea, priapism US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents and young adults |
| amitriptyline (PO) | Elavil | Tricyclic antidepressant (TCA) | MDD, diabetic neuropathy, migraine prophylaxis | Key side effects: dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, dry mouth, blurred vision, constipation. Boxed warning: ↑ suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop. |
| nortriptyline (PO) | Pamelor | Tricyclic antidepressant (TCA) | MDD, diabetic neuropathy, migraine prophylaxis | Key side effects: dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, dry mouth, blurred vision, constipation. Boxed warning: ↑ suicidal thoughts/behavior. Notes: CI within 14 days of MAOI; avoid abrupt stop. |
| doxepin (PO) | Silenor | Tricyclic antidepressant (TCA) | Insomnia | Key Side Effects: somnolence, sedation, nausea US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other Notes: CI within 14 days of MAOI; do not discontinue abruptly |