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Pain, Hema, Onc 2

Pharmacalogic CategoryGenericBrandClassificationCommon Indication Key side effectsUS Boxed WarningOther notes
Opioid and nonopioid analgesic combination hydrocodone and acetaminophen (PO) Lortab, Vicodin, Norco CS-II Pain dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) (See BDK list) use with CYP3A4 inhibitors (or stopping CYP3A4 inducers) can increase oxycodone concentrations; hepatotoxicity n/a
Opioid and nonopioid analgesic combination oxycodone and acetaminophen (PO) Percocet, Endocet CS-II Pain dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) (See BDK list) use with CYP3A4 inhibitors (or stopping CYP3A4 inducers) can increase oxycodone concentrations; hepatotoxicity n/a
Opioid and nonopioid analgesic combination codeine and acetaminophen (PO) Tylenol with Codeine #3, Tylenol with Codeine #4 CS-III Pain dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) See BDK List n/a
Opioid antagonist naloxone (IV, IM, SQ, intranasal) Narcan Nasal Spray, Zimhi Narcan Nasal Spray: OTC Opioid overdose opioid withdrawal syndrome in opioid-dependent populations, pain n/a n/a
Partial opioid agonist and opioid antagonist buprenorphine and naloxone (SL) Suboxone CS-III Opioid use disorder opioid withdrawal syndrome in opioid-dependent populations, constipation, headache, diaphoresis n/a potentially life-threatening respiratory depression (when combined with other CNS and respiratory depressants); addition of naloxone to buprenorphine reduces the possibility of parenteral misuse by producing opioid withdrawal symptoms when injected
Iron supplement ferrous sulfate (PO) FeroSul, SlowFe OTC Iron deficiency anemia nausea, stomach upset, constipation (dose-related), dark and tarry stools accidental overdose of iron is leading cause of fatal poisoning in children under 6 years old n/a
Water-soluble vitamin cyanocobalamin (vitamin B12) (PO, IM, SL, intranasal) n/a PO, SL: OTC Vitamin B12 deficiency (manifests as macrocytic anemia) no major side effects n/a n/a
Water-soluble vitamin folic acid (PO) n/a OTC Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy no major side effects n/a n/a
Created by: ziad5
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