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Endocrine 2

Pharmacologic CategoryGenericBrand Common IndicationKey side effectsUS boxed warningsOther notes
Contraceptive drospirenone and ethinyl estradiol (PO) Yasmin 28, Yaz Contraception, acne nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain increased risk of cardiovascular events in women >35 years old who smoke CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease
Contraceptive levonorgestrel and ethinyl estradiol (PO) Lutera, Levora, Seasonique Contraception, acne nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain increased risk of cardiovascular events in women >35 years old who smoke CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease
Contraceptive norethindrone and ethinyl estradiol (PO) Junel, Loestrin, Microgestin Contraception, acne nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain increased risk of cardiovascular events in women >35 years old who smoke CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease
Contraceptive norethindrone, ethinyl estradiol, and ferrous fumarate (PO) Lo Loestrin Fe, Microgestin Fe Contraception, acne nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain increased risk of cardiovascular events in women >35 years old who smoke CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease
Contraceptive norgestimate and ethinyl estradiol (PO) Tri-Sprintec, Sprintec Contraception, acne nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain increased risk of cardiovascular events in women >35 years old who smoke CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease
Contraceptive norgestrel and ethinyl estradiol (PO) Crysell-28, Low-Ogestrel Contraception, acne nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain increased risk of cardiovascular events in women >35 years old who smoke CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease
Estrogen derivative estrogens, conjugated (equine) (PO, topical) Premarin Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause irritation at application site (transdermal patch only), edema, abdominal pain, breast tenderness, weight gain, thromboembolic disorders (myocardial infarction, stroke, VTE) increased risk of breast cancer; should not be used for dementia prevention; increased risk of endometrial cancer if not used concomitantly with progestin in women with a uterus; should not be used for prevention of cardiovascular disease CI in hepatic dysfunction, thromboembolic disorders, cardiovascular disease, breast cancer, and estrogen-dependent tumor
Estrogen derivative estradiol (transdermal, PO) Transdermal: Climera, Vivelle Dot PO: Estrace Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause irritation at application site (transdermal patch only), edema, abdominal pain, breast tenderness, weight gain, thromboembolic disorders (myocardial infarction, stroke, VTE) increased risk of breast cancer; should not be used for dementia prevention; increased risk of endometrial cancer if not used concomitantly with progestin in women with a uterus; should not be used for prevention of cardiovascular disease CI in hepatic dysfunction, thromboembolic disorders, cardiovascular disease, breast cancer, and estrogen-dependent tumor
Progestin medroxyprogesterone (PO) Provera Abnormal uterine bleeding, secondary amenorrhea acne, abnormal menstrual bleeding, headache, amenorrhea, weight gain increased risk of breast cancer; should not be used for dementia prevention; should not be used for prevention of cardiovascular disease CI in thromboembolic disorders, cardiovascular disease, estrogen or progesterone-dependent tumors, undiagnosed abnormal genital bleeding, hepatic impairment
Created by: ziad5
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