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Pain,Hem, Oncology 2

GenericBrandCategoryIndicationEKEK +
hydrocodone and acetaminophen (PO) Lortab, Vicodin, Norco Opioid and nonopioid analgesic combination Pain Key Side Effects: dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) US Boxed Warnings (all opioid analgesics): See above US Boxed Warnings: use with CYP3A4 inhibitors (or stopping CYP3A4 inducers) can increase oxycodone concentrations; hepatotoxicity
oxycodone and acetaminophen (PO Percocet, Endocet Opioid and nonopioid analgesic combination Pain Key Side Effects: dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) US Boxed Warnings (all opioid analgesics): See above US Boxed Warnings: use with CYP3A4 inhibitors (or stopping CYP3A4 inducers) can increase oxycodone concentrations; hepatotoxicity
codeine and acetaminophen (PO) Tylenol with Codeine #3, Tylenol with Codeine #4 Opioid and nonopioid analgesic combination Pain Key Side Effects: dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) US Boxed Warnings: use or discontinuation of CYP3A4 inducers/inhibitors or 2D6 inhibitors requires caution; may alter codeine levels and ↑ toxicity risk; respiratory depression and death in ultra-rapid metabolizer children; risk of hepatotoxicity.
naloxone (IV, IM, SQ, intranasal) Narcan Nasal Spray, Zimhi Opioid antagonist Opioid overdose Key Side Effects: opioid withdrawal syndrome in opioid-dependent populations, pain
buprenorphine and naloxone (SL) Suboxone Partial opioid agonist and opioid antagonist Opioid use disorder Key Side Effects: opioid withdrawal syndrome in opioid-dependent populations, constipation, headache, diaphoresis Other Notes: life-threatening respiratory depression may occur when combined with CNS or respiratory depressants; adding naloxone to buprenorphine lowers misuse risk by causing opioid withdrawal if injected.
ferrous sulfate (PO) FeroSul Iron supplement Iron deficiency anemia Key Side Effects: nausea, stomach upset, constipation (dose-related), dark and tarry stools US Boxed Warning: accidental overdose of iron is leading cause of fatal poisoning in children under 6 years old
cyanocobalamin (vitamin B12) (PO, IM, SL, intranasal) B-12 Water-soluble vitamin Vitamin B12 deficiency (manifests as macrocytic anemia) Key Side Effects: no major side effects
folic acid (PO) FA Water-soluble vitamin Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy Key Side Effects: no major side effects
Created by: PharmacistJulian
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