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Endo 2
| Generic | Brand | Category | Indication | EK |
|---|---|---|---|---|
| drospirenone and ethinyl estradiol (PO) | Yasmin 28, Yaz | Contraceptive | Contraception, acne | Key Side Effects: nausea, menstrual changes, breast tenderness, headache, weight gain, thromboembolic risk. US Boxed Warning: ↑ CV events in women >35 who smoke. Notes: CI in hepatic dysfunction, VTE, breast CA, migraines w/ aura, CVD |
| levonorgestrel and ethinyl estradiol (PO) | Lutera, Levora, Seasonique | Contraceptive | Contraception, acne | Key Side Effects: nausea, menstrual changes, breast tenderness, headache, weight gain, thromboembolic risk. US Boxed Warning: ↑ CV events in women >35 who smoke. Notes: CI in hepatic dysfunction, VTE, breast CA, migraines w/ aura, CVD |
| norethindrone and ethinyl estradiol (PO) | Junel, Loestrin, Microgestin | Contraceptive | Contraception, acne | Key Side Effects: nausea, menstrual changes, breast tenderness, headache, weight gain, thromboembolic risk. US Boxed Warning: ↑ CV events in women >35 who smoke. Notes: CI in hepatic dysfunction, VTE, breast CA, migraines w/ aura, CVD |
| norethindrone, ethinyl estradiol, and ferrous fumarate (PO) | Lo Loestrin Fe, Microgestin Fe | Contraceptive | Contraception, acne | Key Side Effects: nausea, menstrual changes, breast tenderness, headache, weight gain, thromboembolic risk. US Boxed Warning: ↑ CV events in women >35 who smoke. Notes: CI in hepatic dysfunction, VTE, breast CA, migraines w/ aura, CVD |
| norgestimate and ethinyl estradiol (PO) | Tri-Sprintec, Sprintec | Contraceptive | Contraception, acne | Key Side Effects: nausea, menstrual changes, breast tenderness, headache, weight gain, thromboembolic risk. US Boxed Warning: ↑ CV events in women >35 who smoke. Notes: CI in hepatic dysfunction, VTE, breast CA, migraines w/ aura, CVD |
| norgestrel and ethinyl estradiol (PO) | Crysell-28, Low-Ogestrel | Contraceptive | Contraception, acne | Key Side Effects: nausea, menstrual changes, breast tenderness, headache, weight gain, thromboembolic risk. US Boxed Warning: ↑ CV events in women >35 who smoke. Notes: CI in hepatic dysfunction, VTE, breast CA, migraines w/ aura, CVD |
| estrogens, conjugated (equine) (PO, topical) | Premarin | Estrogen derivative | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | Key Side Effects: site irritation (patch), edema, abdominal pain, breast tenderness, weight gain, thromboembolic events (MI, stroke, VTE). US Boxed Warnings: ↑ risk of breast/endometrial CA, CVD, dementia. Notes: CI in hepatic dz, VTE, CVD, breast CA. |
| estradiol (transdermal, PO) | Transdermal: Climera, Vivelle Dot PO: Estrace | Estrogen derivative | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | Key Side Effects: site irritation (patch), edema, abdominal pain, breast tenderness, weight gain, thromboembolic events (MI, stroke, VTE). US Boxed Warnings: ↑ risk of breast/endometrial CA, CVD, dementia. Notes: CI in hepatic dz, VTE, CVD, breast CA. |
| medroxyprogesterone (PO) | Provera | Progestin | Abnormal uterine bleeding, secondary amenorrhea | Key Side Effects: acne, abnormal bleeding, headache, amenorrhea, weight gain. US Boxed Warnings: ↑ risk of breast CA; not for dementia or CVD prevention. Notes: CI in VTE, CVD, hormone-dependent tumors, unexplained bleeding, hepatic impairment. |