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Pharmacology Chp 1&2
Pharmacy Tech JATC
| Question | Answer |
|---|---|
| What is the term used to describe the process of achieving a system of control and feedback mechanisms that cause the body to keep its self in balance? | homeostasis |
| What does a messenger molecule bind with to cause some effect on the target cell? | receptor |
| The principal way in which cells communicate is through the action of | chemical messengers. |
| Which of the following terms refers to the strength by which a particular messenger binds to its receptor site? | affinity |
| Which of the following terms is used to describe a beta-blocker? | antagonists |
| Which of the following is an example of how an agonist drug works? | One substance attaches to a receptor site. |
| What is the term used to describe the way a drug works within the body to affect both normal physiology and disease? | pharmacokinetics |
| In which of the following pharmacokinetic processes do chemical constituents of drugs make their way into the bloodstream? | absorption |
| Which of the following routes of administration do not require time for absorption because the drug is immediately present in the systemic blood circulation? | intravenous |
| Where is the primary site of absorption for many drugs? | small intestines |
| Which of the following statements best describes bioavailability? | The fraction of an administered dose that is available to the target tissue |
| Which area of the body does most elimination occur? | kidneys |
| A ___________ is the quantity of a drug administered at one time, where a ___________ refers to the administration of a specific amount of drug. | dose; dosage |
| Which of the following terms is used to describe metabolism in the liver before a drug reaches the systemic circulation? | first-pass effect |
| Drug tolerance would describe when | a patient on painkillers needs an ever-increasing dose for relief |
| What term implies a longer duration of the drug action? | duration of action |
| What is the term used to describe a secondary response to a drug other than the primary therapeutic effect that the drug was intended to produce? | side effect |
| What drug class is commonly used for its side effect of drowsiness? | antihistamines |
| Which type of fruit commonly interferes with proper absorption of several common drugs? | grapefruit |
| A substance that produces an allergic response is know as an ___________ and a molecule that stimulates an immune response is know as an __________. | allergen; antigen |
| A(n) _____ makes the prescriber aware of serious problems that have occurred with a drug since it has been on the market. Found at the top of the package insert, it is considered to be the sternest warning | black box warning |
| What is the name of the first official listing of drugs in the United States? | the Pharmacopeia of the United States |
| Which bacteriologist was responsible for discovering penicillin? | Alexander Fleming |
| Which term is used to describe when a patient does not follow the instructions for taking his or her medication(s) properly? | nonadherence |
| The manufacturer’s proprietary right to the drug expires as soon as the patent expires, leaving other companies free to produce a _____ drug. | generic |
| The Food, Drug, and Cosmetic Act of 1938 required that all new drugs be _____before being marketed. | safe |
| What does the FDA require retail pharmacies to distribute that contain specific risk information to patients with certain medications? | boxed warning |
| During some clinical trials, patients in the control group may receive a _____, an inactive substance that the patient believes is a medication but has no pharmacologic effect. | placebo |
| Which of the following is a voluntary program run by the FDA for reporting serious adverse events, product problems, or medication errors? | MedWatch |
| The DEA mandates C-III, IV, and V drugs may only be refilled | five |
| What is the name of the form used to order C-II substances? | DEA222 |
| Which of the following is not required of a generic product submitted to the FDA with an abbreviated new drug application? | It must cost the same as the brand-name drug. |
| Which of the following reference resources identifies generics that are therapeutically equivalent? | Orange Book |
| What term is used to describe the type of clinical trial in which neither the participant nor the investigator knows whether the patient is receiving the active ingredient or placebo? | double-blind |
| A rating system devised by the FDA to establish the therapeutic equivalence of generic drugs is the | A/B system |
| What is the term used to describe the use of a drug for a purpose other than the one approved by the FDA? | off -label use |
| If the FDA obtains information regarding safety concerns about a medication, the agency may issue a(n) | drug recall |
| Which of the following references provides a list of biological products and indicates whether the medication is biosimilar or interchangeable to a reference product? | Purple Book |
| Which of the following categories of medications are complex, difficult to replicate, created in a laboratory, and derived from various living organisms such as bacteria, mammals, plants, insects, and birds? | biologic drugs |
| What type of application must a manufacturer file with the FDA prior to marketing a generic product? | abbreviated new drug application |
Created by:
Leo12345
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