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CV 4
| Pharmacgologic Category | Generic | Brand | Classification | Indication | Key Side effects | US Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|---|
| Antiarrhythmic | amiodarone (PO, IV) | Pacerone, Nexterone | n/a | AF (rhythm control), ventricular fibrillation, ventricular tachycardia | hypothyroidism, hyperthyroidism, pulmonary toxicity, hepatotoxicity, epithelial keratopathy, photosensitivity | intended only for life-threatening arrhythmias; pulmonary toxicity, hepatotoxicity; proarrhythmic | many drug interactions |
| Cholesterol absorption inhibitor | ezetimibe (PO) | Zetia | n/a | Dyslipidemia | myalgias, diarrhea | n/a | n/a |
| Fibric acid derivative | fenofibrate (PO) | Tricor, Trilipix | n/a | Hypertriglyceridemia | dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases | n/a | n/a |
| Fibric acid derivative | gemfibrozil (PO) | Lopid | n/a | Hypertriglyceridemia | dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases | n/a | n/a |
| HMG-CoA reductase inhibitor | atorvastatin (PO) | Lipitor | n/a | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | n/a | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| HMG-CoA reductase inhibitor | lovastatin (PO) | Altoprev | n/a | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | n/a | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| HMG-CoA reductase inhibitor | pravastatin (PO) | Pravachol | n/a | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | n/a | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| HMG-CoA reductase inhibitor | rosuvastatin (PO) | Crestor | n/a | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | n/a | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| HMG-CoA reductase inhibitor | simvastatin (PO) | Zocor | n/a | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | n/a | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| Omega-3 fatty acids | omega-3 ethyl esters (PO) | Lovaza | OTC: available Rx: Lovaza & Vascepa | Hypertriglyceridemia | dyspepsia, eructation, fishy aftertaste | n/a | can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |
| Omega-3 fatty acids | icosapent ethyl (PO) | Vascepa | OTC: available Rx: Lovaza & Vascepa | Hypertriglyceridemia | eructation, arthralgia | n/a | can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |