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Oxygen Transport -

Oxygen Transport - HCCRT

Hypoxic Hypoxia Low PaO2
Anemic Hypoxia Decreased Hb or O2 carrying capacity of Hb.
Circulatory Hypoxia - Cardiac Insufficent pulmonary blood flow
Circulatory Hypoxia - Stagnant Decrease or absent blood flow to tissue cells. Also, arterial-venous shunting: Blood bypasses tissue cells.
Polycythemia Increased amount of RBC's in response to chronic hypoxemia. Resulting blood viscosity increase (thick blood)offsets some beneficial effects by increasing myocardial work.
Cyanosis A blueish discoloration of the skin or mucosa caused by hypoxemia. Technical definition > 5 gm% of reduced Hb.
Digital Clubbing Chronic Pulmonary Osteoarthropathy - Diagnosis made by dissapearance of normal finger/nailbed angle.
Arterial Blood Gas (ABG) Measurement of the gases in the arterial blood which is on it's way back from the lungs going to the various body parts & tissues.
Arterial Blood Gas (ABG) Lower in CO2 and higher in O2.
Arterial Blood Gas (ABG) Tells how good a job the lungs are doing removing CO2 and providing O2.
Normal Arterial Blood Gas Value - pH 7.35 - 7.45
Normal Arterial Blood Gas Value - PCO2 35-45 mmHg (PaCO2)
Normal Arterial Blood Gas Value - HCO3 22-28 mEq/L
Normal Arterial Blood Gas Value - PO2 80-100 mmHg (PaO2)
Normal Arterial Blood Gas Value - BE +/- 2.0
Blood Gas Analyzer Analyzes pH, PCO2, PO2, BE, & SaO2 estimated.
Co-Oximeter Analyzes Hb, COHb, MetHb & SaO2 measured.
Oxygent Content Calculation (CaO2) (gm%Hgb x 1.34) x SaO2 + (.003 x PaO2)
O2 may be dissolved in plasma. When carried this way, it exerts a partial pressure and is expressed as: PaO2
What is the more commonly used lab value? PaO2
What lab value is more meaningful and a better assesment of the patients oxygentation status? SaO2
Where do you get the PaO2 value from? ABG
Where do you get the SaO2 value from? Co-Oximetry
Oxyhemoglobin Dissociation Curve Illustrates the % of hemoglobin that is chemically bound to oxygen at each oxygen pressure.
Shunt Cardiac output that reaches left heart without having exchanged gases in the alveoli.
True/Absolute Shunt - Anatomic Blood flow from the right to the left heart without perfusing alveoli.
True/Absolute Shunt - Capillary Perfusion of unventilated alveoli.
Shunt-Like Effect Caused by impaired ventilation and/or perfusion.
Venous Admixture End result of pulmonary shunting.
Oxygen Dissociation Curve (or Oxygen–Hemoglobin Dissociation Curve) Plots the proportion of hemoglobin in its saturated form on the vertical axis against the prevailing oxygen tension on the horizontal axis.
CaO2 = (gm% Hgb x 1.34) x SaO2 + (0.003 x Pa02)
How is most of our oxygen carried? Bound to Hemoglobin
Abnormal Hemoglobin - Deoxygenated/Reduced Hemoglobin that has reduced or no oxygen
Abnormal Hemoglobin - Fetal Fetal & Newborn Hemoglobin
Abnormal Hemoglobin - Carboxyhemoglobin Carbon Monoxide & Hemoglobin
Abnormal Hemoglobin - Methemoglobin Met Molecule & Hemoglobin
Bohr Effect States that an increasing concentration of protons and/or carbon dioxide will reduce the oxygen affinity of hemoglobin.
A-aDO2 {(PB - PHO2) x FiO2} - PaCO2 x 1.25
Created by: CLPRRT