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Gastroenterology 1

GenericBrandCategoryIndicationEssential Knowledge
dicyclomine (PO) Bentyl Anticholinergic; Antispasmodic IBS Key Side Effects: drowsiness, blurred vision, dizziness, xerostomia, constipation Other Notes: CI in gastrointestinal obstruction, reflux esophagitis, acute hemorrhage with cardiac instability, obstructive uropathy, glaucoma
linaclotide (PO) Linzess Guanylate cyclase C agonist IBS-C, opioid-induced constipation Key Side Effects: diarrhea, abdominal pain US Boxed Warnings: do not use in patients <2 years of age (risk of death due to dehydration) Other Notes: mechanical gastrointestinal obstruction
polyethylene glycol 3350 (PO) MiraLax Osmotic laxative Constipation Key Side Effects: abdominal cramping, electrolyte imbalance Other Notes: CI with bowel obstruction
Lactulose (PO) Enulose, Constulose Osmotic laxative Constipation, hepatic encephalopathy Key Side Effects: abdominal cramps, abdominal distention, diarrhea, flatulence
senna (PO) Ex-Lax, Senokot Stimulant laxative Constipation Key Side Effects: abdominal cramping, electrolyte imbalance
docusate (PO) Colace Stool softener Prevent straining during defecation Other Notes: do not use with mineral oil
dexamethasone (PO, IV) DexPak, DoubleDex Corticosteroid nflammatory diseases, cerebral edema, CINV Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
methylprednisolone (PO, IM, IV) Medrol, Solu-medrol Corticosteroid Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
prednisolone (PO) Orapred Corticosteroid Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
prednisone (PO) Deltasone, Rayos Corticosteroid Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
hydrocortisone (PO, IV, topical) Topical: Cortaid IV: Solu-Cortef Corticosteroid Topical: Inflammation, rash PO/IV: Acute illness, adrenal insufficiency Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
Created by: PharmacistJulian
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