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GI 1

Pharmacologic CategoryGenericBrandClassificationCommon IndicationKey Side EffectsUS Boxed WarningsOther Notes
Anticholinergic; Antispasmodic dicyclomine (PO) Bentyl n/a IBS drowsiness, blurred vision, dizziness, xerostomia, constipation n/a CI in gastrointestinal obstruction, reflux esophagitis, acute hemorrhage with cardiac instability, obstructive uropathy, glaucoma
Guanylate cyclase C agonist linaclotide (PO) Linzess n/a IBS-C, opioid-induced constipation diarrhea, abdominal pain do not use in patients <2 years of age (risk of death due to dehydration) mechanical gastrointestinal obstruction
Osmotic laxative polyethylene glycol 3350 (po) MiraLax OTC Constipation abdominal cramping, electrolyte imbalance n/a CI with bowel obstruction
Osmotic laxative Lactulose (PO) Enulose, Constulose n/a Constipation, hepatic encephalopathy abdominal cramps, abdominal distention, diarrhea, flatulence n/a n/a
Stimulant laxative senna (PO) Ex-Lax, Senokot OTC Constipation abdominal cramping, electrolyte imbalance n/a n/a
Stool softener docusate (PO) Colace OTC Prevent straining during defecation n/a n/a do not use with mineral oil
Corticosteroid dexamethasone (PO, IV) DexPak, DoubleDex n/a Inflammatory diseases, cerebral edema, CINV hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) n/a risk of adrenal suppression with prolonged use
Corticosteroid methylprednisolone (PO, IM, IV) Medrol, Solu-Medrol n/a Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) n/a risk of adrenal suppression with prolonged use
Corticosteroid prednisolone (PO) Orapred n/a Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) n/a risk of adrenal suppression with prolonged use
Corticosteroid prednisone (PO) Deltasone, Rayos n/a Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) n/a risk of adrenal suppression with prolonged use
Corticosteroid hydrocortisone (PO, IV, topical) Topical: Cortaid IV: Solu-Cortef Topical: OTC Topical: Inflammation, rash PO/IV: Acute illness, adrenal insufficiency hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) n/a risk of adrenal suppression with prolonged use
Created by: ziad5
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